ADAM12 Antibody

• Catalog number
  bs-4977R
• Price
  Please ask
• Size
  0.1ml

• Long name
  ADAM12 Primary Polyclonal Antibody
• Also known as
  ADAM12 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  ADAM12
• Specificity
  This is a highly specific antibody against ADAM12.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ADAM12/MLTN
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases that are involved in cell-cell, cell-matrix interface related processes including fertilization, muscle fusion, secretion of TNF?(tumor necrosis factor ?, and modulation of the neurogenic function of Notch and Delta (1-3). ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (Integrin ligand), a cysteine-rich region, an epidermal growth factor-like domain, a transmembrane domain and a cytoplasmic tail (1-3). ADAMs are expressed in brain, testis, epididymis, ovary, breast, placenta, liver, heart, lung, bone, and muscle, and catalyze proteolysis, adhesion, fusion, and intracellular signaling (3). ADAM 12 (Meltrin-a) is produced as 2 differentially spliced isoforms, a 718 amino acid secreted form (ADAM12S) and a 881 amino acid membrane-bound form (ADAM12L), and is involved in egg-sperm fusion (4-6).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  MLTN; A disintegrin and metalloproteinase domain 12; A disintegrin and metalloproteinase domain 12; ADA12_HUMAN; ADAM 12; ADAM metallopeptidase domain 12; ADAM12; Disintegrin and metalloproteinase domain-containing protein 12; MCMP; MCMPMltna; MCMPMltna; Meltrin alpha; Meltrin-alpha; MLTN; MLTNA; OTTHUMP00000046766.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ADAM12  
• Gene symbol
  ADAM12
• Short name
  Anti-ADAM12
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  ADAM12 Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  ADAM metallopeptidase domain 12, ADAM12-OT1 and CAR10 and MCMP and MCMPMltna and MLTN and MLTNA, ADAM12 and IDBG-93032 and ENSG00000148848 and 8038, SH3 domain binding, Extracellular, Adam12 and IDBG-211287 and ENSMUSG00000054555 and 11489, BT.29890 and IDBG-640937 and ENSBTAG00000012444 and 407229

Gene info

• Identity
  HGNC:190
• Gene
  ADAM12
• Long gene name
  ADAM metallopeptidase domain 12
• Synonyms gene name
  • a disintegrin and metalloproteinase domain 12 (meltrin alpha)
• Synonyms
  • MCMPMltna
  • MLTN
• Synonyms name
  • meltrin alpha
• GenBank acession
  • AF023476
• Locus
  10q26.2
• Discovery year
  1998-12-01
• Entrez gene record
  8038
• Pubmed identfication
  • 9417060
  • 18342566
• Classification
  • ADAM metallopeptidase domain containing
• VEGA ID
  OTTHUMG00000019243

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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