TRPV1/VR1 Antibody, Cy5 Conjugated

• Catalog number
  bs-1931R-Cy5
• Price
  Please ask
• Size
  0.1ml

• Long name
  TRPV1/VR1 Polyclonal Antibody, Cy5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  TRPV1/VR1
• Specificity
  This is a highly specific antibody against TRPV1/VR1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  800-839/839
• Subcellular location
  Cytoplasm
• Source
  KLH conjugated synthetic peptide derived from human VR1
• Gene ID number
  7442
• Swiss Prot
  Q8NER1
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin. Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects. Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis (By similarity). Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca(2+)-dependent outward rectification, followed by a long-lasting refractory state. Mild extracellular acidic pH (6.5) potentiates channel activation by noxious heat and vanilloids, whereas acidic conditions (pH
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  625,650nm/670nm
• Synonyms
  VR1; Transient receptor potential cation channel subfamily V member 1; TrpV1; Capsaicin receptor; Osm-9-like TRP channel 1; OTRPC1; Vanilloid receptor 1
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5
• French translation
  anticorps

• Gene target
  TRPV1/VR1   Conjugated  
• Gene symbol
  TRPV1, VTRNA1-1
• Short name
  Anti-TRPV1/VR1
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5
• Alternative name
  Anti-TRPV1/VR1 PAb Cy5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:12716
• Gene
  TRPV1
• Long gene name
  transient receptor potential cation channel subfamily V member 1
• Synonyms gene
  • VR1
• Synonyms gene name
  • vanilloid receptor subtype 1
  • transient receptor potential cation channel, subfamily V, member 1
• GenBank acession
  • AJ272063
• Locus
  17p13.2
• Discovery year
  1997-12-05
• Entrez gene record
  7442
• Pubmed identfication
  • 9349813
  • 11549313
  • 16382100
• RefSeq identity
  • NM_018727
• Classification
  • Ankyrin repeat domain containing
  • Transient receptor potential cation channels
• VEGA ID
  OTTHUMG00000177649

Gene info

• Identity
  HGNC:12654
• Gene
  VTRNA1-1
• Long gene name
  vault RNA 1-1
• Synonyms gene
  • VAULTRC1
• Synonyms gene name
  • vault RNA component 1
• Synonyms
  • hvg-1
  • HVG1
  • vRNA
  • VR1
• GenBank acession
  • AF045143
  • BD247418
• Locus
  5q31.3
• Discovery year
  2000-07-31
• Entrez gene record
  56664
• Pubmed identfication
  • 9535882
  • 19298825
  • 19491402
  • 30773316
• RefSeq identity
  • NR_026703
• Classification
  • Vault RNAs

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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