SB-366791, TRPV1 blocker

• Catalog number
  SIH-321-50MG
• Price
  Please ask
• Size
  50 mg

• Stock availabilitIn Stock
  In Stock
• CAS number
  472981-92-3
• Description
  TRPV1 blocker
• Molecular weight
  287,75 g/mol
• Primary research fields
  Neuroscience, Ion Channels, Transient Receptor Potential Channels
• Other name
  (2E)-3-(4-Chlorophenyl)-N-(3-methoxyphenyl)acrylamide, N-(3-Methoxyphenyl)-4-chlorocinnamide
• Product category
  Small Molecules
• Product type
  Inhibitor
• Chemical formula
  C16H14CINO2
• Origin
  Synthetic
• Purity pourcentage
  >98%
• Soluble in
  Soluble to 10 mM in ethanol and to 100 mM in DMSO
• Physical appearance
  White solid
• Storage recommendations
  -20ºC
• Shipping recommendations
  Shipped Ambient
• Safety information
  Classification: Caution: Substance not fully tested yet. Safety Phrases: S22 - Do not breathe dust S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S24/25- Avoid contact with shin and eyes
• PubChem number
  667594
• Scientific context
  A potent and selective vanilloid receptor (TRPV1) antagonist. An effective antagonist of hTRPV1 when stimulated by capsaicin, acid, or noxious heat.
• Bibliography
  1.  Gunthorpe M.J., et al. (2004) Neuropharmacology. 46(1): 133-149.
• Release date
  16-May-2011
• PubMed number
  Refer to PubMed
• Tested applications
  To be tested
• Tested reactivity
  To be tested
• Representative figure link
• Representative figure legend
  Chemical structure of SB-366791 (SIH-321), a TRPV1 blocker. CAS #: 472981-92-3. Molecular Formula: C16H14CINO2. Molecular Weight: 287.75 g/mol. Chemical structure of SB-366791, a TRPV1 blocker (SIH-321). CAS # 472981-92-3. Molecular Formula: C16H14CINO2.
• Warning information
  Non-hazardous
• Country of production
  Canada
• Total weight kg
  0.25
• Net weight g
  0.05
• Other related products

• Gene target
  SB-366791   TRPV1   blocker  
• Gene symbol
  TRPV1
• Short name
  SB-366791, TRPV1 blocker
• Alternative name
  SB-366791, TRPV1 blocker

Gene info

• Identity
  HGNC:12716
• Gene
  TRPV1
• Long gene name
  transient receptor potential cation channel subfamily V member 1
• Synonyms gene
  • VR1
• Synonyms gene name
  • vanilloid receptor subtype 1
  • transient receptor potential cation channel, subfamily V, member 1
• GenBank acession
  • AJ272063
• Locus
  17p13.2
• Discovery year
  1997-12-05
• Entrez gene record
  7442
• Pubmed identfication
  • 9349813
  • 11549313
  • 16382100
• RefSeq identity
  • NM_018727
• Classification
  • Ankyrin repeat domain containing
  • Transient receptor potential cation channels
• VEGA ID
  OTTHUMG00000177649

Similar products