TAB1 Antibody, FITC Conjugated

• Catalog number
  bs-4135R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  TAB1 Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  TAB1
• Specificity
  This is a highly specific antibody against TAB1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human MAP3K7IP1/TAB1
• Gene ID number
  10454
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta and members of the Toll IL 1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. This protein, together with either TAB2 or TAB3, activates TAK1 kinase in response to upstream signals. It has been shown that the C terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N terminus acts as a dominant negative inhibitor of TGF beta, demonstrating how this protein can function as a mediator between TGF beta receptors and TAK1.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; Mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TGF-beta-activated kinase 1-binding protein 1; TAK1-binding protein 1; TAB1; MAP3K7IP1
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  TAB1   Conjugated  
• Gene symbol
  TAB1
• Short name
  Anti-TAB1
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-TAB1 PAb FITC
• Alternative technique
  antibodies, fluorescine
• Alternative to gene target
  TGF-beta activated kinase 1/MAP3K7 binding protein 1, 3\'-Tab1 and MAP3K7IP1, TAB1 and IDBG-8281 and ENSG00000100324 and 10454, mitogen-activated protein kinase p38 binding, nuclei, Tab1 and IDBG-163423 and ENSMUSG00000022414 and 66513, MAP3K7IP1 and IDBG-641725 and ENSBTAG00000019828 and 519958

Gene info

• Identity
  HGNC:18157
• Gene
  TAB1
• Long gene name
  TGF-beta activated kinase 1 (MAP3K7) binding protein 1
• Synonyms gene
  • MAP3K7IP1
• Synonyms gene name
  • mitogen-activated protein kinase kinase kinase 7 interacting protein 1
  • TGF-beta activated kinase 1/MAP3K7 binding protein 1
• Synonyms name
  • TAK1-binding protein 1
  • mitogen-activated protein kinase kinase kinase 7 interacting protein 1
• GenBank acession
  • U49928
• Locus
  22q13.1
• Discovery year
  2002-02-22
• Entrez gene record
  10454
• Pubmed identfication
  • 8638164
  • 10187861
• RefSeq identity
  • NM_153497
• VEGA ID
  OTTHUMG00000151102

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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