SLC6A4/5-HTT Antibody, FITC Conjugated
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Catalog numberbs-1893R-FITC
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PricePlease ask
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Size0.1ml
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Long nameSLC6A4/5-HTT Polyclonal Antibody, FITC Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationFITC
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenSLC6A4/5-HTT
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SpecificityThis is a highly specific antibody against SLC6A4/5-HTT.
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ModificationUnmodified
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Modification siteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Immunogen_range436-464/630
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Subcellular locationCytoplasm
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SourceKLH conjugated synthetic peptide derived from human 5-HTT
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Gene ID number6532
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Swiss ProtP31645
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen backgroundSerotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission494nm/518nm
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SynonymsHTT; 5HTT; OCD1; SERT; 5-HTT; SERT1; hSERT; 5-HTTLPR; Sodium-dependent serotonin transporter; 5HT transporter; Solute carrier family 6 member 4; SLC6A4
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
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Additional conjugationAnti-FITC Antibody
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French translationanticorps
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Gene target
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Gene symbolSLC6A4, HTT-AS, HTT, MIR1302-5, PIRC22, PIRC23, PIRC20, PIRC21, HTR6, IGKV3OR2-5
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Short nameAnti-SLC6A4/5-HTT
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TechniqueAntibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
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IsotypeImmunoglobulin G (IgG)
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LabelFITC
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Alternative nameAnti-SLC6A4/5-HTT PAb FITC
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Alternative techniqueantibodies, fluorescine
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Alternative to gene targethuntingtin, HD and IT15, HTT and IDBG-7852 and ENSG00000197386 and 3064, diazepam binding, nuclei, Htt and IDBG-156033 and ENSMUSG00000029104 and 15194, HTT and IDBG-643549 and ENSBTAG00000001506 and 615059
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Gene info
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Identity
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Gene
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Long gene namesolute carrier family 6 member 4
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Synonyms gene
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Synonyms gene name
- solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
- 5-hydroxytryptamine (serotonin) transporter
- obsessive-compulsive disorder 1
- solute carrier family 6 (neurotransmitter transporter), member 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1994-03-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Solute carriers
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameHTT antisense RNA
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Synonyms gene
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Synonyms gene name
- HTT antisense RNA 1 (non-protein coding)
- HTT antisense RNA 1
- HTT antisense RNA (head to head)
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Synonyms
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Locus
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Discovery year2011-06-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namehuntingtin
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Synonyms gene
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Synonyms gene name
- huntingtin (Huntington disease)
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Synonyms
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
- Armadillo like helical domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1302-5
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1302 family
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 22
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 23
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 20
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 21
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene name5-hydroxytryptamine receptor 6
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Synonyms gene name
- 5-hydroxytryptamine (serotonin) receptor 6
- 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-12-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- 5-hydroxytryptamine receptors, G protein-coupled
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 3/OR2-5 (pseudogene)
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Synonyms gene name
- immunoglobulin kappa variable 3/OR2-5
- immunoglobulin kappa variable 3/OR2-5 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
