RAI1/Retinoid acid induced protein 1 Antibody, Biotin Conjugated

• Catalog number
  bs-11940R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  RAI1/Retinoid acid induced protein 1 Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  RAI1/Retinoid acid induced protein 1
• Specificity
  This is a highly specific antibody against RAI1/Retinoid acid induced protein 1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human RAI1/Retinoid acid induced protein 1
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Retinoic acid induced 1 (RAI1) is a 1,906 amino acid protein containing an N-terminal polyglutamine stretch that is expressed in most tissues, with highest expression in neuronal tissues. RAI1 functions as a transcriptional regulator and is important for embryonic and postnatal developments. Heterozygous deletions of the RAI1 gene are associated with Smith-Magenis syndrome (SMS), a mental retardation syndrome with behavioral, neurological and skeletal anomalies. Individuals affected with SMS usually display self-injurious behaviors, sleep disturbance, developmental delay and reduced motor and cognitive skills. RAI1 haploinsufficiency is specifically responsible for the obesity and craniofacial symptoms of SMS. RAI1 mutations have also been implicated in schizophrenia and spinocerebellar ataxia type 2.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  DKFZP434A139; KIAA1820; MGC12824; retinoic acid induced 1; Retinoid acid induced protein 1; SMCR; SMS; RAI1_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• Description
  Induced protein genes, factors or kinases, increase the production of (an enzyme or other protein) at the level of genetic transcription.
• French translation
  anticorps

• Gene target
  RAI1/Retinoid   acid   protein   Conjugated  
• Gene symbol
  RAI1-AS1, RNASE12, RAI1
• Short name
  Anti-RAI1/Retinoid acid induced protein 1
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-RAI1/Retinoid acid induced protein 1 PAb Biotin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:40496
• Gene
  RAI1-AS1
• Long gene name
  RAI1 antisense RNA 1
• Synonyms gene name
  • RAI1 antisense RNA 1 (non-protein coding)
• GenBank acession
  • BX366317
  • BX401587
• Locus
  17p11.2
• Discovery year
  2011-12-05
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000059315

Gene info

• Identity
  HGNC:24211
• Gene
  RNASE12
• Long gene name
  ribonuclease A family member 12 (inactive)
• Synonyms gene name
  • ribonuclease, RNase A family, 12 (non-active)
• Synonyms
  • RAI1
• Locus
  14q11.2
• Discovery year
  2004-12-03
• Entrez gene record
  493901
• Pubmed identfication
  • 15676279
• Classification
  • Ribonuclease A family
• VEGA ID
  OTTHUMG00000170991

Gene info

• Identity
  HGNC:9834
• Gene
  RAI1
• Long gene name
  retinoic acid induced 1
• Synonyms gene
  • SMCR
• Synonyms gene name
  • Smith-Magenis syndrome chromosome region
• Synonyms
  • DKFZP434A139
  • SMS
  • KIAA1820
  • MGC12824
• GenBank acession
  • AJ230819
• Locus
  17p11.2
• Discovery year
  1999-04-16
• Entrez gene record
  10743
• Pubmed identfication
  • 10036180
• RefSeq identity
  • NM_030665
• VEGA ID
  OTTHUMG00000059314

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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