Anti-RAI1/Retinoid acid induced protein 1, ALEXA Fluor 594
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Catalog numberGENTObs-11940R-A594
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PricePlease ask
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Size100 microliters
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TypeConjugated Primary Antibody
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Conjugated withALEXA FLUOR® 594
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Host organismRabbit (Oryctolagus cuniculus)
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Target Protein PeptideRAI1/Retinoid acid induced protein 1
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SpecificityThis antibody reacts specifically with RAI1/Retinoid acid induced protein 1
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ModificationNo modification has been applied to this antibody
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Modification siteNone
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ClonalityPolyclonal Antibody
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ClonePolyclonal Antibodies
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Concentration1ug per 1ul
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Subcellular locationsN/A
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Antigen SourceKLH conjugated synthetic peptide derived from human RAI1/Retinoid acid induced protein 1
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Gene IDN/A
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Swiss ProtN/A
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ApplicationsIF(IHC-P)
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Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
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Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
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Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
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Background informationRetinoic acid induced 1 (RAI1) is a 1,906 amino acid protein containing an N-terminal polyglutamine stretch that is expressed in most tissues, with highest expression in neuronal tissues. RAI1 functions as a transcriptional regulator and is important for embryonic and postnatal developments. Heterozygous deletions of the RAI1 gene are associated with Smith-Magenis syndrome (SMS), a mental retardation syndrome with behavioral, neurological and skeletal anomalies. Individuals affected with SMS usually display self-injurious behaviors, sleep disturbance, developmental delay and reduced motor and cognitive skills. RAI1 haploinsufficiency is specifically responsible for the obesity and craniofacial symptoms of SMS. RAI1 mutations have also been implicated in schizophrenia and spinocerebellar ataxia type 2.
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Purification methodPurified by Protein A.
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StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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Excitation emission590nm/617nm
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SynonymsDKFZP434A139; KIAA1820; MGC12824; retinoic acid induced 1; Retinoid acid induced protein 1; SMCR; SMS; RAI1_HUMAN.
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Also known asRAI1/Retinoid acid induced protein 1 Antibody
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Other nameAnti-RAI1/Retinoid acid induced protein 1
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AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesFor facs or microscopy Alexa 1 conjugate.
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ConjugationAlexa Fluor, ALEXA FLUOR® 594
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ConjugatedAlexa conjugate 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Induced protein genes, factors or kinases, increase the production of (an enzyme or other protein) at the level of genetic transcription.
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Gene target
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Gene symbolRAI1-AS1, RNASE12, RAI1
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Short nameAnti-RAI1/Retinoid acid induced protein 1
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Techniqueanti-, anti, antibody to, antibodies
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 594
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Alternative nameRAI1/Retinoid acid induced protein 1 Antibody, ALEXA FLUOR® 594 Conjugated
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameRAI1 antisense RNA 1
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Synonyms gene name
- RAI1 antisense RNA 1 (non-protein coding)
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GenBank acession
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Locus
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Discovery year2011-12-05
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Classification
- Antisense RNAs
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameribonuclease A family member 12 (inactive)
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Synonyms gene name
- ribonuclease, RNase A family, 12 (non-active)
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Synonyms
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Locus
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Discovery year2004-12-03
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Entrez gene record
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Pubmed identfication
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Classification
- Ribonuclease A family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameretinoic acid induced 1
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Synonyms gene
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Synonyms gene name
- Smith-Magenis syndrome chromosome region
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-04-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data