PKC beta 1/2 (Thr500) Antibody, Cy5 Conjugated

• Catalog number
  bs-2505R-Cy5
• Price
  Please ask
• Size
  0.1ml

• Long name
  PKC beta 1/2 (Thr500) Antibody, Cy5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  PRKCB Thr500
• Specificity
  This is a highly specific antibody against PRKCB Thr500.
• Modification
  Phosphorylation
• Modification site
  Thr500
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  490-520/671
• Source
  KLH conjugated synthetic peptide derived from human PRKCB around the phosphorylation site of Thr500
• Gene ID number
  5579
• Swiss Prot
  P05771
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  625,650nm/670nm
• Synonyms
  PKCB; PRKCB1; PRKCB2; PKC-beta; Protein kinase C beta type; PKC-B; PRKCB
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5
• French translation
  anticorps

• Gene target
  PKC   beta   1/2   Thr500   Conjugated  
• Gene symbol
  PRKCH, PRKD1, PRRT2, PRKDC
• Short name
  Anti-PRKCB Thr500
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5
• Alternative name
  Anti-PRKCB Thr500 PAb Cy5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:9403
• Gene
  PRKCH
• Long gene name
  protein kinase C eta
• Synonyms gene
  • PRKCL
• Synonyms gene name
  • protein kinase C, eta
• Synonyms
  • PKC-L
  • PKCL
• GenBank acession
  • M55284
• Locus
  14q23.1
• Discovery year
  1992-06-26
• Entrez gene record
  5583
• Pubmed identfication
  • 1986216
  • 1545821
• RefSeq identity
  • NM_006255
• Classification
  • C2 domain containing protein kinases
  • AGC family kinases
• VEGA ID
  OTTHUMG00000152341

Gene info

• Identity
  HGNC:9407
• Gene
  PRKD1
• Long gene name
  protein kinase D1
• Synonyms gene
  • PRKCM
• Synonyms gene name
  • protein kinase C, mu
• Synonyms
  • PKCM
  • PKD
  • PKC-mu
• Locus
  14q12
• Discovery year
  1994-05-16
• Entrez gene record
  5587
• Pubmed identfication
  • 8119958
  • 10965134
• RefSeq identity
  • NM_002742
• Classification
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000140203

Gene info

• Identity
  HGNC:30500
• Gene
  PRRT2
• Long gene name
  proline rich transmembrane protein 2
• Synonyms gene
  • ICCA
  • DYT10
• Synonyms gene name
  • infantile convulsions and paroxysmal choreoathetosis
  • dystonia 10
  • proline-rich transmembrane protein 2
• Synonyms
  • FLJ25513
  • DKFZp547J199
  • IFITMD1
  • FICCA
  • DSPB3
  • PKC
  • EKD1
• Synonyms name
  • interferon induced transmembrane protein domain containing 1
  • dispanin subfamily B member 3
• GenBank acession
  • BC011405
• Locus
  16p11.2
• Discovery year
  2005-11-25
• Entrez gene record
  112476
• Pubmed identfication
  • 22101681
  • 22243967
  • 29346777
• RefSeq identity
  • NM_145239
• Classification
  • interferon induced transmembrane protein domain containing
• VEGA ID
  OTTHUMG00000177142

Gene info

• Identity
  HGNC:9413
• Gene
  PRKDC
• Long gene name
  protein kinase, DNA-activated, catalytic subunit
• Synonyms gene
  • HYRC
  • HYRC1
• Synonyms gene name
  • protein kinase, DNA-activated, catalytic polypeptide
• Synonyms
  • DNPK1
  • p350
  • DNAPK
  • XRCC7
  • DNA-PKcs
  • DNAPKc
  • DNA-PKC
  • p460
• Synonyms name
  • DNA-dependent protein kinase catalytic subunit
• Locus
  8q11.21
• Discovery year
  1993-11-09
• Entrez gene record
  5591
• Pubmed identfication
  • 7638222
• RefSeq identity
  • NM_001081640
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000164239
• Locus Specific Databases
  • LRG_162

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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