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PKC gamma (Thr514) Antibody, Cy5 Conjugated

  • Catalog number
    bs-3729R-Cy5
  • Product name
    PKC gamma (Thr514) Antibody, Cy5 Conjugated
  • Size
    0.1ml
  • Short name
    Anti-PKC gamma Thr514
  • Long name
    PKC gamma (Thr514) Polyclonal Antibody, Cy5 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Cy5
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    PKC gamma Thr514
  • Specificity
    This is a highly specific antibody against PKC gamma Thr514.
  • Modification
    Phosphorylation
  • Modification site
    Thr514
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Immunogen range
    500-540/697
  • Subcellular location
    Cytoplasm
  • Source
    KLH conjugated synthetic phosphopeptide derived from human PKC gamma around the phosphorylation site of Thr514
  • Gene ID number
    5582
  • Swiss Prot
    P05129
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). [provided by RefSeq, Jul 2008]
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    625,650nm/670nm
  • Synonyms
    PKCC; PKCG; SCA14; PKC-gamma; Protein kinase C gamma type; PRKCG
  • Gene target
    PKC gamma Thr514 Conjugated
    • Gene info
    Gene info
    Gene info
    Gene info
    Locus Specific Databases:LRG_162
  • Gene symbol
    PRKCH, PRKD1, PRRT2, PRKDC
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    Cy5
  • label filter
    • Cy5
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Alternative technique
    antibodies