OPA1 Antibody, FITC Conjugated

• Catalog number
  bs-11764R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  OPA1 Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  OPA1
• Specificity
  This is a highly specific antibody against OPA1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  680-725/960
• Subcellular location
  Mitochondrion
• Source
  KLH conjugated synthetic peptide derived from human OPA1
• Gene ID number
  84692
• Swiss Prot
  Q8NEL0
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  OPA1 is a 120kDa protein belonging to the dynamin family. The OPA1 gene has been localized to 3q29. The gene is targeted to mitochondria and is involved in mitochondrial biogenesis. Defects in OPA1 are a cause of optic atrophy type 1. OPA1 is mostly expressed in retina but can also be expressed in brain, testis, heart and skeletal muscle.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  SP17; NYD-SP17; Coiled-coil domain-containing protein 54; Testis development protein NYD-SP17; CCDC54
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  OPA1   Conjugated  
• Gene symbol
  OPA1-AS1, OPA1, MED12
• Short name
  Anti-OPA1
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-OPA1 PAb FITC
• Alternative technique
  antibodies, fluorescine
• Alternative to gene target
  optic atrophy 1 (autosomal dominant), largeG and MGM1 and NPG and NTG, OPA1 and IDBG-70072 and ENSG00000198836 and 4976, GTP binding, Plasma membranes, Opa1 and IDBG-151468 and ENSMUSG00000038084 and 74143, OPA1 and IDBG-634327 and ENSBTAG00000019514 and 524142

Gene info

• Identity
  HGNC:40421
• Gene
  OPA1-AS1
• Long gene name
  OPA1 antisense RNA 1
• Synonyms gene name
  • OPA1 antisense RNA 1 (non-protein coding)
• Locus
  3q29
• Discovery year
  2011-07-27
• Entrez gene record
  100873941
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000156072

Gene info

• Identity
  HGNC:8140
• Gene
  OPA1
• Long gene name
  OPA1 mitochondrial dynamin like GTPase
• Synonyms gene name
  • optic atrophy 1 (autosomal dominant)
  • OPA1, mitochondrial dynamin like GTPase
• Synonyms
  • NTG
  • KIAA0567
  • FLJ12460
  • NPG
  • MGM1
• Synonyms name
  • mitochondrial dynamin-like GTPase
  • dynamin-like guanosine triphosphatase
  • Dynamin-like 120 kDa protein, mitochondrial
• GenBank acession
  • AB011139
• Locus
  3q29
• Discovery year
  1987-09-11
• Entrez gene record
  4976
• Pubmed identfication
  • 9490303
• RefSeq identity
  • NM_130837
• VEGA ID
  OTTHUMG00000149897
• Locus Specific Databases
  • Mutations of the Optic Atrophy 1 Gene
  • LRG_337

Gene info

• Identity
  HGNC:11957
• Gene
  MED12
• Long gene name
  mediator complex subunit 12
• Synonyms gene
  • TNRC11
  • FGS1
• Synonyms gene name
  • trinucleotide repeat containing 11 (THR-associated protein, 230kDa subunit)
  • mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae)
  • FG syndrome 1
• Synonyms
  • CAGH45
  • HOPA
  • OPA1
  • TRAP230
  • KIAA0192
  • OKS
  • ARC240
  • Kto
• Synonyms name
  • Kohtalo homolog
• GenBank acession
  • U80742
• Locus
  Xq13.1
• Discovery year
  2000-01-27
• Entrez gene record
  9968
• Pubmed identfication
  • 9225980
  • 10198638
  • 17334363
  • 20507344
• RefSeq identity
  • NM_005120
• Classification
  • Mediator complex
• VEGA ID
  OTTHUMG00000021788
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products