OPA1 Antibody, ALEXA FLUOR 488

• Catalog number
  bs-11764R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  OPA1 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-OPA1 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  OPA1
• Specificity
  This is a highly specific antibody against OPA1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  680-725/960
• Subcellular location
  Mitochondrion
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OPA1
• Gene ID Number
  84692
• Swiss Prot
  Q8NEL0
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  OPA1 is a 120kDa protein belonging to the dynamin family. The OPA1 gene has been localized to 3q29. The gene is targeted to mitochondria and is involved in mitochondrial biogenesis. Defects in OPA1 are a cause of optic atrophy type 1. OPA1 is mostly expressed in retina but can also be expressed in brain, testis, heart and skeletal muscle.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  SP17; NYD-SP17; Coiled-coil domain-containing protein 54; Testis development protein NYD-SP17; CCDC54
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-OPA1 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  OPA1  
• Gene symbol
  OPA1-AS1, OPA1, MED12
• Short name
  Anti-OPA1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  OPA1 Polyclonal Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies
• Alternative to gene target
  optic atrophy 1 (autosomal dominant), largeG and MGM1 and NPG and NTG, OPA1 and IDBG-70072 and ENSG00000198836 and 4976, GTP binding, Plasma membranes, Opa1 and IDBG-151468 and ENSMUSG00000038084 and 74143, OPA1 and IDBG-634327 and ENSBTAG00000019514 and 524142

Gene info

• Identity
  HGNC:40421
• Gene
  OPA1-AS1
• Long gene name
  OPA1 antisense RNA 1
• Synonyms gene name
  • OPA1 antisense RNA 1 (non-protein coding)
• Locus
  3q29
• Discovery year
  2011-07-27
• Entrez gene record
  100873941
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000156072

Gene info

• Identity
  HGNC:8140
• Gene
  OPA1
• Long gene name
  OPA1 mitochondrial dynamin like GTPase
• Synonyms gene name
  • optic atrophy 1 (autosomal dominant)
  • OPA1, mitochondrial dynamin like GTPase
• Synonyms
  • NTG
  • KIAA0567
  • FLJ12460
  • NPG
  • MGM1
• Synonyms name
  • mitochondrial dynamin-like GTPase
  • dynamin-like guanosine triphosphatase
  • Dynamin-like 120 kDa protein, mitochondrial
• GenBank acession
  • AB011139
• Locus
  3q29
• Discovery year
  1987-09-11
• Entrez gene record
  4976
• Pubmed identfication
  • 9490303
• RefSeq identity
  • NM_130837
• VEGA ID
  OTTHUMG00000149897
• Locus Specific Databases
  • Mutations of the Optic Atrophy 1 Gene
  • LRG_337

Gene info

• Identity
  HGNC:11957
• Gene
  MED12
• Long gene name
  mediator complex subunit 12
• Synonyms gene
  • TNRC11
  • FGS1
• Synonyms gene name
  • trinucleotide repeat containing 11 (THR-associated protein, 230kDa subunit)
  • mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae)
  • FG syndrome 1
• Synonyms
  • CAGH45
  • HOPA
  • OPA1
  • TRAP230
  • KIAA0192
  • OKS
  • ARC240
  • Kto
• Synonyms name
  • Kohtalo homolog
• GenBank acession
  • U80742
• Locus
  Xq13.1
• Discovery year
  2000-01-27
• Entrez gene record
  9968
• Pubmed identfication
  • 9225980
  • 10198638
  • 17334363
  • 20507344
• RefSeq identity
  • NM_005120
• Classification
  • Mediator complex
• VEGA ID
  OTTHUMG00000021788
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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