JUP/gamma Catenin Antibody, FITC Conjugated

• Catalog number
  bs-1720R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  JUP/gamma Catenin Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  JUP/gamma Catenin
• Specificity
  This is a highly specific antibody against JUP/gamma Catenin. This antibody may have minor cross-reactivity with catenin beta-1 based upon 75% non-contiguous sequence similarity.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  630-680/745
• Subcellular location
  Cell membrane
• Source
  KLH conjugated synthetic peptide derived from human Cateninma gamma
• Gene ID number
  3728
• Swiss Prot
  P14923
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  DP3; PDGB; PKGB; CTNNG; DPIII; ARVD12; Junction plakoglobin; Catenin gamma; Desmoplakin III; Desmoplakin-3; JUP
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  JUP/gamma   Catenin   Conjugated  
• Gene symbol
  JUP
• Short name
  Anti-JUP/gamma Catenin
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-JUP/gamma Catenin PAb FITC
• Alternative technique
  antibodies, fluorescine
• Alternative to gene target
  junction plakoglobin, ARVD12 and CTNNG and DP3 and DPIII and PDGB and PKGB, JUP and IDBG-49784 and ENSG00000173801 and 3728, cadherin binding, nuclei, Jup and IDBG-211364 and ENSMUSG00000001552 and 16480, JUP and IDBG-640020 and ENSBTAG00000017685 and 445543

Gene info

• Identity
  HGNC:6207
• Gene
  JUP
• Long gene name
  junction plakoglobin
• Synonyms gene
  • CTNNG
• Synonyms gene name
  • catenin (cadherin-associated protein), gamma 80kDa
• Synonyms
  • DP3
  • PDGB
  • PKGB
  • DPIII
  • PG
• Synonyms name
  • desmosomal protein 3
• GenBank acession
  • AF233882
• Locus
  17q21.2
• Discovery year
  1991-03-04
• Entrez gene record
  3728
• Pubmed identfication
  • 1889810
  • 7604000
• RefSeq identity
  • NM_001352773
• Classification
  • Beta catenins
  • Armadillo repeat containing
• VEGA ID
  OTTHUMG00000133494
• Locus Specific Databases
  • Gene Connection for the Heart; Naxos disease database
  • Global Variome shared LOVD
  • LRG_401

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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