HCCS Antibody, FITC Conjugated

• Catalog number
  bs-15424R-FITC
• Price
  Please ask
• Size
  0.1ml

• Long name
  HCCS Polyclonal Antibody, FITC Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  FITC
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  HCCS
• Specificity
  This is a highly specific antibody against HCCS.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human HCCS
• Gene ID number
  3052
• Swiss Prot
  P53701
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  HCCS is a 79 amino acid protein that may act as a tumor suppressor, promoting the apoptosis of cancer cells. Expressed in leukocytes, lung, spleen, liver, heart, kidney, muscle and uterine cervix, HCCS-1 is down-regulated in cervical cancers. The gene encoding HCCS-1 maps to human chromosome 15q25.1. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and comprises about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  494nm/518nm
• Synonyms
  CCHL; DKFZp779I1858; EC 4.4.1.17; Holocytochrome c synthase cytochrome c heme lyase; Holocytochrome c type synthase; MCOPS7; OTTHUMP00000022903; OTTHUMP00000022904; OTTHUMP00000022905; OTTMUSP00000021173; OTTMUSP00000021174; RGD1563855; RP23-37L2.1; CCHL_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
• Additional conjugation
  Anti-FITC Antibody
• French translation
  anticorps

• Gene target
  HCCS   Conjugated  
• Gene symbol
  HCCS-DT, ST20, HCCS
• Short name
  Anti-HCCS
• Technique
  Antibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
• Isotype
  Immunoglobulin G (IgG)
• Label
  FITC
• Alternative name
  Anti-HCCS PAb FITC
• Alternative technique
  antibodies, fluorescine

Gene info

• Identity
  HGNC:55698
• Gene
  HCCS-DT
• Long gene name
  HCCS divergent transcript
• Locus
  Xp22.2
• Discovery year
  2021-07-05
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:33520
• Gene
  ST20
• Long gene name
  suppressor of tumorigenicity 20
• Synonyms
  • HCCS-1
• Synonyms name
  • human cervical cancer suppressor 1
• GenBank acession
  • AF249277
• Locus
  15q25.1
• Discovery year
  2007-07-16
• Entrez gene record
  400410
• Pubmed identfication
  • 11857354
• VEGA ID
  OTTHUMG00000172078

Gene info

• Identity
  HGNC:4837
• Gene
  HCCS
• Long gene name
  holocytochrome c synthase
• Synonyms gene
  • MLS
• Synonyms gene name
  • holocytochrome c synthase (cytochrome c heme-lyase)
  • microphthalmia with linear skin defects
• Synonyms
  • CCHL
• Synonyms name
  • cytochrome c heme-lyase
  • holocytochrome-c synthetase
• Locus
  Xp22.2
• Discovery year
  1995-09-20
• Entrez gene record
  3052
• Pubmed identfication
  • 8364577
  • 12444108
• Classification
  • Mitochondrial respiratory chain complex assembly factors
• VEGA ID
  OTTHUMG00000021128
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Fluorescent Antibody Technique
• Concept
  Scope note: Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
• Tree numbers
  • E01.370.225.500.607.512.240
  • E01.370.225.750.551.512.240
  • E05.200.500.607.512.240
  • E05.200.750.551.512.240
  • E05.478.583.375
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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