HCCS Antibody, Biotin Conjugated

• Catalog number
  bs-15424R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  HCCS Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  HCCS
• Specificity
  This is a highly specific antibody against HCCS.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from human HCCS
• Gene ID number
  3052
• Swiss Prot
  P53701
• Tested applications
  IHC-P
• Recommended dilutions
  IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  HCCS is a 79 amino acid protein that may act as a tumor suppressor, promoting the apoptosis of cancer cells. Expressed in leukocytes, lung, spleen, liver, heart, kidney, muscle and uterine cervix, HCCS-1 is down-regulated in cervical cancers. The gene encoding HCCS-1 maps to human chromosome 15q25.1. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and comprises about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  CCHL; DKFZp779I1858; EC 4.4.1.17; Holocytochrome c synthase cytochrome c heme lyase; Holocytochrome c type synthase; MCOPS7; OTTHUMP00000022903; OTTHUMP00000022904; OTTHUMP00000022905; OTTMUSP00000021173; OTTMUSP00000021174; RGD1563855; RP23-37L2.1; CCHL_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  HCCS   Conjugated  
• Gene symbol
  HCCS-DT, ST20, HCCS
• Short name
  Anti-HCCS
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-HCCS PAb Biotin
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:55698
• Gene
  HCCS-DT
• Long gene name
  HCCS divergent transcript
• Locus
  Xp22.2
• Discovery year
  2021-07-05
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:33520
• Gene
  ST20
• Long gene name
  suppressor of tumorigenicity 20
• Synonyms
  • HCCS-1
• Synonyms name
  • human cervical cancer suppressor 1
• GenBank acession
  • AF249277
• Locus
  15q25.1
• Discovery year
  2007-07-16
• Entrez gene record
  400410
• Pubmed identfication
  • 11857354
• VEGA ID
  OTTHUMG00000172078

Gene info

• Identity
  HGNC:4837
• Gene
  HCCS
• Long gene name
  holocytochrome c synthase
• Synonyms gene
  • MLS
• Synonyms gene name
  • holocytochrome c synthase (cytochrome c heme-lyase)
  • microphthalmia with linear skin defects
• Synonyms
  • CCHL
• Synonyms name
  • cytochrome c heme-lyase
  • holocytochrome-c synthetase
• Locus
  Xp22.2
• Discovery year
  1995-09-20
• Entrez gene record
  3052
• Pubmed identfication
  • 8364577
  • 12444108
• Classification
  • Mitochondrial respiratory chain complex assembly factors
• VEGA ID
  OTTHUMG00000021128
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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