FOXA2/HNF 3beta Antibody, HRP Conjugated

• Catalog number
  bs-2358R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  FOXA2/HNF 3beta Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  FOXA2/HNF 3beta
• Specificity
  This is a highly specific antibody against FOXA2/HNF 3beta.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  200-250/457
• Subcellular location
  Cytoplasm, Nucleus
• Source
  KLH conjugated synthetic peptide derived from human HNF 3 beta
• Gene ID number
  3170
• Swiss Prot
  Q9Y261
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  HNF3B; TCF3B; Hepatocyte nuclear factor 3-beta; HNF-3-beta; HNF-3B; Forkhead box protein A2; Transcription factor 3B; TCF-3B; FOXA2
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  FOXA2/HNF   3beta   Conjugated  
• Gene symbol
  FOXA2, ONECUT1, FOXM1
• Short name
  Anti-FOXA2/HNF 3beta
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-FOXA2/HNF 3beta PAb HRP
• Alternative technique
  antibodies
• Alternative to gene target
  forkhead box A2, HNF3B and TCF3B, FOXA2 and IDBG-59234 and ENSG00000125798 and 3170, transcription regulatory region DNA binding, nuclei, Foxa2 and IDBG-208945 and ENSMUSG00000037025 and 15376, FOXA2 and IDBG-648756 and ENSBTAG00000012407 and 503580

Gene info

• Identity
  HGNC:5022
• Gene
  FOXA2
• Long gene name
  forkhead box A2
• Synonyms gene
  • HNF3B
• Synonyms gene name
  • hepatocyte nuclear factor 3, beta
• GenBank acession
  • AF147787
• Locus
  20p11.21
• Discovery year
  1998-02-11
• Entrez gene record
  3170
• Pubmed identfication
  • 9119385
  • 11875061
• Classification
  • Forkhead boxes
• VEGA ID
  OTTHUMG00000191876

Gene info

• Identity
  HGNC:8138
• Gene
  ONECUT1
• Long gene name
  one cut homeobox 1
• Synonyms gene
  • HNF6
  • HNF6A
• Synonyms gene name
  • one cut domain, family member 1
• Synonyms
  • HNF-6
• GenBank acession
  • U77975
• Locus
  15q21.3
• Discovery year
  2000-02-11
• Entrez gene record
  3175
• Pubmed identfication
  • 8887657
  • 8790352
• Classification
  • CUT class homeoboxes and pseudogenes
• VEGA ID
  OTTHUMG00000131899

Gene info

• Identity
  HGNC:3818
• Gene
  FOXM1
• Long gene name
  forkhead box M1
• Synonyms gene
  • FKHL16
• Synonyms
  • HFH-11
  • trident
  • HNF-3
  • INS-1
  • MPP2
  • MPHOSPH2
  • TGT3
• Synonyms name
  • M-phase phosphoprotein 2
• GenBank acession
  • Y12773
• Locus
  12p13.33
• Discovery year
  1997-07-25
• Entrez gene record
  2305
• Pubmed identfication
  • 9032290
  • 9441747
• RefSeq identity
  • NM_021953
• Classification
  • Forkhead boxes
• VEGA ID
  OTTHUMG00000168118

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products