EMR1 Antibody, Biotin Conjugated

• Catalog number
  bs-7058R-Biotin
• Price
  Please ask
• Size
  0.1ml

• Long name
  EMR1 Polyclonal Antibody, Biotin Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Biotin
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  EMR1
• Specificity
  This is a highly specific antibody against EMR1.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  732-747/886
• Subcellular location
  Extracellular
• Source
  KLH conjugated synthetic peptide derived from human EMR1
• Gene ID number
  2015
• Swiss Prot
  Q14246
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL (1–3). These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system (1–3). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1,3,4). The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria, and Langerhans cells in the skin (1). F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5,6). The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration, or as a G-protein coupled signaling component of macrophages.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  TM7LN3; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-like module receptor 1; EMR1 hormone receptor; EMR1
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Additional conjugation
  Biotinylated
• French translation
  anticorps

• Gene target
  EMR1   Conjugated  
• Gene symbol
  ADGRE1
• Short name
  Anti-EMR1
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Biotin
• Alternative name
  Anti-EMR1 PAb Biotin
• Alternative technique
  antibodies
• Alternative to gene target
  egf-like module containing, mucin-like, hormone receptor-like 1, TM7LN3, EMR1 and IDBG-22184 and ENSG00000174837 and 2015, protein binding, Cell surfaces, Emr1 and IDBG-194190 and ENSMUSG00000004730 and 13733, EMR1 and IDBG-643875 and ENSBTAG00000007901 and

Gene info

• Identity
  HGNC:3336
• Gene
  ADGRE1
• Long gene name
  adhesion G protein-coupled receptor E1
• Synonyms gene
  • TM7LN3
  • EMR1
• Synonyms gene name
  • egf-like module containing, mucin-like, hormone receptor-like sequence 1
  • egf-like module containing, mucin-like, hormone receptor-like 1
• GenBank acession
  • X81479
• Locus
  19p13.3-p13.2
• Discovery year
  1994-08-31
• Entrez gene record
  2015
• Pubmed identfication
  • 7601460
  • 9500513
  • 25713288
• Classification
  • Adhesion G protein-coupled receptors, subfamily E
• VEGA ID
  OTTHUMG00000181966

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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