EMR1 Antibody, ALEXA FLUOR 594

• Catalog number
  bs-7058R-A594
• Price
  Please ask
• Size
  100ul

• Long name
  EMR1 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
• Also known as
  Anti-EMR1 PAb ALEXA FLUOR 594
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 594
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  EMR1
• Specificity
  This is a highly specific antibody against EMR1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  732-747/886
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EMR1
• Gene ID Number
  2015
• Swiss Prot
  Q14246
• Tested applications
  FCM, IF(IHC-P)
• Recommended dilutions
  FCM(1:20-100), IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL (1–3). These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system (1–3). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1,3,4). The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria, and Langerhans cells in the skin (1). F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5,6). The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration, or as a G-protein coupled signaling component of macrophages.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  590nm/617nm
• Synonyms
  TM7LN3; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-like module receptor 1; EMR1 hormone receptor; EMR1
• Properties
  For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• French translation
  anticorps

• Gene target
  EMR1  
• Gene symbol
  ADGRE1
• Short name
  Anti-EMR1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  EMR1 Polyclonal Antibody, ALEXA FLUOR 594
• Alternative technique
  antibodies
• Alternative to gene target
  egf-like module containing, mucin-like, hormone receptor-like 1, TM7LN3, EMR1 and IDBG-22184 and ENSG00000174837 and 2015, protein binding, Cell surfaces, Emr1 and IDBG-194190 and ENSMUSG00000004730 and 13733, EMR1 and IDBG-643875 and ENSBTAG00000007901 and

Gene info

• Identity
  HGNC:3336
• Gene
  ADGRE1
• Long gene name
  adhesion G protein-coupled receptor E1
• Synonyms gene
  • TM7LN3
  • EMR1
• Synonyms gene name
  • egf-like module containing, mucin-like, hormone receptor-like sequence 1
  • egf-like module containing, mucin-like, hormone receptor-like 1
• GenBank acession
  • X81479
• Locus
  19p13.3-p13.2
• Discovery year
  1994-08-31
• Entrez gene record
  2015
• Pubmed identfication
  • 7601460
  • 9500513
  • 25713288
• Classification
  • Adhesion G protein-coupled receptors, subfamily E
• VEGA ID
  OTTHUMG00000181966

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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