DOK1 (Ser450) Antibody, Cy5 Conjugated
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Catalog number
bs-13027R-Cy5
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Price
Please ask
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Size
0.1ml
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Long name
DOK1 (Ser450) Polyclonal Antibody, Cy5 Conjugated
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Category
Conjugated Primary Antibodies
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Conjugation
Cy5
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
DOK1 Ser450
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Specificity
This is a highly specific antibody against DOK1 Ser450.
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Modification
Phosphorylation
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Modification site
Ser450
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
KLH conjugated synthetic phosphopeptide derived from human DOK1 around the phosphorylation site of Ser450
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Gene ID number
1796
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen background
Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission
625,650nm/670nm
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Synonyms
DOK1 phospho S450; DOK1 phospho Ser450; p-DOK1 phospho S450; docking protein 1 downstream of tyrosine kinase 1; Docking protein 1 p62dok Downstream of tyrosine kinase 1 pp62; docking protein 1 62kD downstream of tyrosine kinase 1; Docking protein 1 62kD; Docking protein 1 62kD; Docking protein 1; DOK 1; DOK1; DOK-1; DOK1_HUMAN; Downstream of tyrosine kinase 1; p62dok; P62DOK; pp62; pp62.
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Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
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Additional conjugation
Cy5.5
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French translation
anticorps
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Gene target
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Gene symbol
DOK1, ART4
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Short name
Anti-DOK1 Ser450
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Technique
Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
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Isotype
Immunoglobulin G (IgG)
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Label
Cy5
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Alternative name
Anti-DOK1 Ser450 PAb Cy5
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Alternative technique
antibodies
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Alternative to gene target
docking protein 1, 62kDa (downstream of tyrosine kinase 1), P62DOK, DOK1 and IDBG-57879 and ENSG00000115325 and 1796, protein binding, nuclei, Dok1 and IDBG-159342 and ENSMUSG00000068335 and 13448, DOK1 and IDBG-631228 and ENSBTAG00000018579 and 514962
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Gene info
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Identity
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Gene
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Long gene name
docking protein 1
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Synonyms gene name
- docking protein 1, 62kD (downstream of tyrosine kinase 1)
- docking protein 1, 62kDa (downstream of tyrosine kinase 1)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1997-07-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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