DOK1 (Tyr398) Antibody, HRP Conjugated

• Catalog number
  bs-5290R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  DOK1 (Tyr398) Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  DOK1 Tyr398
• Specificity
  This is a highly specific antibody against DOK1 Tyr398.
• Modification
  Phosphorylation
• Modification site
  Tyr398
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human DOK1 around the phosphorylation site of Tyr398
• Gene ID number
  1796
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  DOK1 phospho Y398; DOK1 phospho Tyr398; p-DOK1 phospho Y398; docking protein 1 downstream of tyrosine kinase 1; Docking protein 1 p62dok Downstream of tyrosine kinase 1 pp62.; docking protein 1 62kD downstream of tyrosine kinase 1; Docking protein 1 62kD; Docking protein 1 62kD; Docking protein 1; DOK 1; DOK1; DOK-1; DOK1_HUMAN; Downstream of tyrosine kinase 1; p62dok; P62DOK; pp62; pp62.
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  DOK1   Tyr398   Conjugated  
• Gene symbol
  DOK1, ART4
• Short name
  Anti-DOK1 Tyr398
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-DOK1 Tyr398 PAb HRP
• Alternative technique
  antibodies
• Alternative to gene target
  docking protein 1, 62kDa (downstream of tyrosine kinase 1), P62DOK, DOK1 and IDBG-57879 and ENSG00000115325 and 1796, protein binding, nuclei, Dok1 and IDBG-159342 and ENSMUSG00000068335 and 13448, DOK1 and IDBG-631228 and ENSBTAG00000018579 and 514962

Gene info

• Identity
  HGNC:2990
• Gene
  DOK1
• Long gene name
  docking protein 1
• Synonyms gene name
  • docking protein 1, 62kD (downstream of tyrosine kinase 1)
  • docking protein 1, 62kDa (downstream of tyrosine kinase 1)
• Synonyms
  • p62dok
• Synonyms name
  • downstream of tyrosine kinase 1
• GenBank acession
  • U70987
• Locus
  2p13.1
• Discovery year
  1997-07-25
• Entrez gene record
  1796
• Pubmed identfication
  • 9008160
  • 9790776
  • 15546884
• RefSeq identity
  • NM_001381
• VEGA ID
  OTTHUMG00000129956

Gene info

• Identity
  HGNC:726
• Gene
  ART4
• Long gene name
  ADP-ribosyltransferase 4 (inactive) (Dombrock blood group)
• Synonyms gene
  • DO
• Synonyms gene name
  • Dombrock blood group
  • ADP-ribosyltransferase 4 (DO blood group)
  • ADP-ribosyltransferase 4
  • ADP-ribosyltransferase 4 (Dombrock blood group)
• Synonyms
  • DOK1
  • CD297
  • ARTC4
• Synonyms name
  • NAD(+)--protein-arginine ADP-ribosyltransferase 4
• GenBank acession
  • X95826
• Locus
  12p12.3
• Discovery year
  1998-05-11
• Entrez gene record
  420
• Pubmed identfication
  • 9119374
• RefSeq identity
  • NM_021071
• Classification
  • Blood group antigens
  • ADP-ribosyltransferase family
  • CD molecules
• VEGA ID
  OTTHUMG00000168738
• Locus Specific Databases
  • LRG_807

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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