DDX5 (Tyr593) Antibody, HRP Conjugated

• Catalog number
  bs-8005R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  DDX5 (Tyr593) Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  DDX5 Tyr593
• Specificity
  This is a highly specific antibody against DDX5 Tyr593.
• Modification
  Phosphorylation
• Modification site
  Tyr593
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  577-605/614
• Subcellular location
  Nucleus
• Source
  KLH conjugated synthetic phosphopeptide derived from human DDX5 around the phosphorylation site of Tyr593
• Gene ID number
  1655
• Swiss Prot
  P17844
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for estrogen receptor ESR1 and androgen receptor AR. Increases ESR1 AF-1 domain-mediated transactivation and ESR1 AF-1 and AF-2 domains transcriptional synergistic activity. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 transcriptional activity and involved in skeletal muscle differentiation. Transcriptional coactivator for p53/TP53 and involved in p53/TP53 transcriptional response to DNA damage and p53/TP53-dependent apoptosis. Transcriptional coactivator for RUNX2 and involved in regulation of osteoblast differentiation. Acts as transcriptional repressor in a promoter-specicic manner; the function probbaly involves association with histone deacetylases, such as HDAC1. As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  p68; HLR1; G17P1; HUMP68; Probable ATP-dependent RNA helicase DDX5; DEAD box protein 5; RNA helicase p68; DDX5; HELR
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  DDX5   Tyr593   Conjugated  
• Gene symbol
  DDX5
• Short name
  Anti-DDX5 Tyr593
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-DDX5 Tyr593 PAb HRP
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2746
• Gene
  DDX5
• Long gene name
  DEAD-box helicase 5
• Synonyms gene
  • HLR1
  • G17P1
• Synonyms gene name
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68kD)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
  • DEAD (Asp-Glu-Ala-Asp) box helicase 5
• Synonyms
  • p68
• GenBank acession
  • AF015812
• Locus
  17q23.3
• Discovery year
  1989-06-30
• Entrez gene record
  1655
• Pubmed identfication
  • 22156369
  • 18698352
• RefSeq identity
  • NM_004396
• Classification
  • DEAD-box helicases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000178936

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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