DDX5 (Tyr593) Antibody, Cy5.5 Conjugated

• Catalog number
  bs-8005R-Cy5.5
• Price
  Please ask
• Size
  0.1ml

• Long name
  DDX5 (Tyr593) Polyclonal Antibody, Cy5.5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5.5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  DDX5 Tyr593
• Specificity
  This is a highly specific antibody against DDX5 Tyr593.
• Modification
  Phosphorylation
• Modification site
  Tyr593
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  577-605/614
• Subcellular location
  Nucleus
• Source
  KLH conjugated synthetic phosphopeptide derived from human DDX5 around the phosphorylation site of Tyr593
• Gene ID number
  1655
• Swiss Prot
  P17844
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for estrogen receptor ESR1 and androgen receptor AR. Increases ESR1 AF-1 domain-mediated transactivation and ESR1 AF-1 and AF-2 domains transcriptional synergistic activity. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 transcriptional activity and involved in skeletal muscle differentiation. Transcriptional coactivator for p53/TP53 and involved in p53/TP53 transcriptional response to DNA damage and p53/TP53-dependent apoptosis. Transcriptional coactivator for RUNX2 and involved in regulation of osteoblast differentiation. Acts as transcriptional repressor in a promoter-specicic manner; the function probbaly involves association with histone deacetylases, such as HDAC1. As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  675nm/694nm
• Synonyms
  p68; HLR1; G17P1; HUMP68; Probable ATP-dependent RNA helicase DDX5; DEAD box protein 5; RNA helicase p68; DDX5; HELR
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5, Cy5.5
• Conjugated
  These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
• French translation
  anticorps

• Gene target
  DDX5   Tyr593   Conjugated  
• Gene symbol
  DDX5
• Short name
  Anti-DDX5 Tyr593
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5.5
• Alternative name
  Anti-DDX5 Tyr593 PAb Cy5.5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2746
• Gene
  DDX5
• Long gene name
  DEAD-box helicase 5
• Synonyms gene
  • HLR1
  • G17P1
• Synonyms gene name
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 5 (RNA helicase, 68kD)
  • DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
  • DEAD (Asp-Glu-Ala-Asp) box helicase 5
• Synonyms
  • p68
• GenBank acession
  • AF015812
• Locus
  17q23.3
• Discovery year
  1989-06-30
• Entrez gene record
  1655
• Pubmed identfication
  • 22156369
  • 18698352
• RefSeq identity
  • NM_004396
• Classification
  • DEAD-box helicases
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000178936

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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