DC-SIGN Antibody, Cy7 Conjugated
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Catalog numberbs-10053R-Cy7
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PricePlease ask
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Size0.1ml
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Long nameDC-SIGN Polyclonal Antibody, Cy7 Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationCy7
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenDC-SIGN
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SpecificityThis is a highly specific antibody against DC-SIGN.
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ModificationUnmodified
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Modification siteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Subcellular locationExtracellular
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SourceKLH conjugated synthetic peptide derived from human DC-SIGN/CD209
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Gene ID number30835
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman
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Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen backgroundDendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration of viral infectivity. Multiple strains of HIV1, HIV2 and SIV bind to DCs via DCSIGN. ICAM3 is the natural ligand for DC-SIGN. A DC-SIGN homologue (termed CD299, DC-SIGNR, L-SIGN and DCSIGN2) was identified recently. DC-SIGN forms a novel gene family with DC-SIGNR and many alternatively spliced isoforms of DC-SIGN and DC-SIGNR. The expression of DC-SIGN was found in mucosal tissues including placenta, small intestine, and rectum.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission743nm/767nm
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SynonymsCLEC4L; Dendritic cell-specic ICAM-3-grabbing non-integrin 1; C type lectin domain family 4 member L; CD 209; CD209; CD209 antigen; CD209 antigen-like protein A; CD209 molecule; Cd209a; CDSIGN; CIRE; DC SIGN1; DCSIGN; Dendritic cell specic ICAM 3 grabbing nonintegrin 1; Dendritic cell specic ICAM3 grabbing nonintegrin 1; Dendritic cell-specic intracellular adhesion molecules ICAM-3 grabbing non-integrin; Dengue fever, protection against, included; Dentritic Cell Specic ICAM3 Grabbing Nonintegrin; HIV GP120 Binding Protein; MGC129965; MGC130443; SIGN-R1; SIGNR5; CD209_HUMAN.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
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Additional conjugationCy7
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French translationanticorps
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Gene target
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Gene symbolCD209, CLEC4M, UBTD2, WFDC21P, TSPAN14, DCSTAMP, DCX, LAMP3, PDCD1LG2, CCL18
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Short nameAnti-DC-SIGN
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TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates
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IsotypeImmunoglobulin G (IgG)
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LabelCy7
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Alternative nameAnti-DC-SIGN PAb Cy7
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameCD209 molecule
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Synonyms gene name
- CD209 antigen
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-07-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptors
- C-type lectin domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameC-type lectin domain family 4 member M
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Synonyms gene
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Synonyms gene name
- CD299 antigen
- C-type lectin domain family 4, member M
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-09-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameubiquitin domain containing 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-11-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameWAP four-disulfide core domain 21, pseudogene
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Synonyms
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Synonyms name
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Locus
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Discovery year2014-06-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nametetraspanin 14
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Synonyms gene
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Synonyms gene name
- transmembrane 4 superfamily member 14
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-10-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tetraspanins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedendrocyte expressed seven transmembrane protein
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Synonyms gene
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Synonyms gene name
- transmembrane 7 superfamily member 4
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-06-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedoublecortin
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Synonyms gene name
- doublecortex; lissencephaly, X-linked (doublecortin)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-03-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Doublecortin superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelysosomal associated membrane protein 3
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Synonyms gene name
- lysosomal-associated membrane protein 3
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-29
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Entrez gene record
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Pubmed identfication
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Classification
- Lysosome associated membrane proteins
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameprogrammed cell death 1 ligand 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-11-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- B7 family
- CD molecules
- Immunoglobulin like domain containing
- Receptor ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameC-C motif chemokine ligand 18
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Synonyms gene
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Synonyms gene name
- small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary and activation-regulated
- chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
- chemokine (C-C motif) ligand 18
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1997-01-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chemokine ligands
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data