Complement C4 gamma chain Antibody, Cy5.5 Conjugated

  • Catalog number
    bs-10454R-Cy5.5
  • Price
    Please ask
  • Size
    0.1ml
  • Long name
    Complement C4 gamma chain Antibody, Cy5.5 Conjugated
  • Category
    Conjugated Primary Antibodies
  • Conjugation
    Cy5.5
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    Complement C4 gamma chain
  • Specificity
    This is a highly specific antibody against Complement C4 gamma chain.
  • Modification
    Unmodified
  • Modification site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Immunogen_range
    1485-1535/1744
  • Subcellular location
    Secreted
  • Source
    KLH conjugated synthetic peptide derived from human Complement C4 gamma chain
  • Gene ID number
    720721
  • Swiss Prot
    P0C0L4
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human
  • Crossreactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Antigen background
    Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
  • Excitation Emission
    675nm/694nm
  • Synonyms
    C4; RG; C4S; CO4; C4A2; C4A3; C4A4; C4A6; C4AD; CPAMD2; CH; C4F; C4B1; C4B2; C4B3; C4B5; C4BD; C4B12; C4B_2; CPAMD3; Complement C4-A; Acidic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C4A
  • Properties
    If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
  • Additional conjugation
    Cy5.5, Cy5.5
  • Conjugated
    These antibodies are excite for emission at 678nm and detected at a 694 nm wavelengths.
  • French translation
    anticorps
  • Gene target
  • Short name
    Anti-Complement C4 gamma chain
  • Technique
    Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    Cy5.5
  • Alternative name
    Anti-Complement C4 gamma chain PAb Cy5.5
  • Alternative technique
    antibodies
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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