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Complement C4 gamma chain Antibody, ALEXA FLUOR 555

  • Catalog number
    bs-10454R-A555
  • Product name
    Complement C4 gamma chain Antibody, ALEXA FLUOR 555
  • Size
    100ul
  • Short name
    Anti-Complement C4 gamma chain
  • Long name
    Complement C4 gamma chain Antibody, ALEXA FLUOR 555 Conjugated
  • Also known as
    Anti-Complement C4 gamma chain PAb ALEXA FLUOR 555
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 555
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    Complement C4 gamma chain
  • Specificity
    This is a highly specific antibody against Complement C4 gamma chain.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Immunogen range
    1485-1535/1744
  • Subcellular location
    Secreted
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Complement C4 gamma chain
  • Gene ID Number
    720721
  • Swiss Prot
    P0C0L4
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Non-enzymatic component of C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens. Derived from proteolytic degradation of complement C4, C4a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    553nm/568nm
  • Synonyms
    C4; RG; C4S; CO4; C4A2; C4A3; C4A4; C4A6; C4AD; CPAMD2; CH; C4F; C4B1; C4B2; C4B3; C4B5; C4BD; C4B12; C4B_2; CPAMD3; Complement C4-A; Acidic complement C4; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2; C4A
  • Gene target
    Complement C4 gamma chain
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    ALEXA FLUOR 555
  • label filter
    • ALEXA FLUOR 555
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies