Centromeric histone H3-like protein-2 Antibody, FITC Conjugated
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Catalog numberbs-0483R-FITC
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PricePlease ask
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Size0.1ml
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Long nameCentromeric histone H3-like protein-2 Antibody, FITC Conjugated
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CategoryConjugated Primary Antibodies
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ConjugationFITC
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenCentromeric histone H3-like protein-2
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SpecificityThis is a highly specific antibody against Centromeric histone H3-like protein-2.
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ModificationUnmodified
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Modification siteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceKLH conjugated synthetic peptide derived from Brassica juncea Centromeric histone H3-like protein-2
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Gene ID number1058
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityPlant
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Crossreactive species detailsBrassica juncea
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Antigen backgroundHistones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission494nm/518nm
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Synonymscentromere-specic H3 variant protein; Centromeric histone H3-like protein 2; Centromeric histone H3-like protein-2; cenp-A; A4P1_BRAJU.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
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Additional conjugationAnti-FITC Antibody
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French translationanticorps
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Gene target
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Gene symbolH3-7, H3C15, H3Y2, H3Y1, H3-4, H3C14, H3C11, H3-3A-DT, H3-5, RLN3
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Short nameAnti-Centromeric histone H3-like protein-2
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TechniqueAntibody, FITC, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
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IsotypeImmunoglobulin G (IgG)
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LabelFITC
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Alternative nameAnti-Centromeric histone H3-like protein-2 PAb FITC
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Alternative techniqueantibodies, fluorescine
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Gene info
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Identity
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Gene
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Long gene nameH3.7 histone (putative)
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Synonyms gene
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Synonyms gene name
- histone 2, H3, pseudogene 2
- histone cluster 2, H3, pseudogene 2
- histone cluster 2 H3 pseudogene 2
- H3.2 histone (putative)
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-06-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH3 clustered histone 15
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Synonyms gene
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Synonyms gene name
- histone 2, H3a
- histone cluster 2, H3a
- histone cluster 2 H3 family member a
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-02-19
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Entrez gene record
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Pubmed identfication
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Classification
- H3 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH3.Y histone 2
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Synonyms
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Locus
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Discovery year2019-08-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
Gene info
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Identity
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Gene
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Long gene nameH3.Y histone 1
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Synonyms
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Locus
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Discovery year2019-08-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
Gene info
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Identity
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Gene
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Long gene nameH3.4 histone
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Synonyms gene
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Synonyms gene name
- H3 histone family, member T
- histone 3, H3
- histone cluster 3, H3
- histone cluster 3 H3
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-09-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH3 clustered histone 14
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Synonyms gene
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Synonyms gene name
- H3 histone family, member M
- histone 2, H3c
- histone cluster 2, H3c
- histone cluster 2 H3 family member c
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-02-19
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH3 clustered histone 11
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Synonyms gene
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Synonyms gene name
- H3 histone family, member F
- histone 1, H3i
- histone cluster 1, H3i
- histone cluster 1 H3 family member i
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH3-3A divergent transcript
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Locus
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Discovery year2020-08-21
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Classification
- Divergent transcripts
Gene info
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Identity
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Gene
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Long gene nameH3.5 histone
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Synonyms gene
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Synonyms gene name
- H3 histone, family 3C
- H3 histone family member 3C
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Synonyms
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GenBank acession
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Locus
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Discovery year2009-08-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namerelaxin 3
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Synonyms gene name
- relaxin 3 (H3)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-11-16
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Entrez gene record
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Classification
- Neuropeptides
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VEGA ID
MeSH Data
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Name
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ConceptScope note: A method for the study of certain organic compounds within cells, in situ, by measuring the light intensities of the selectively stained areas of cytoplasm. The compounds studied and their locations in the cells are made to fluoresce and are observed under a microscope.
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Tree numbers
- E01.370.225.500.386
- E05.196.712.516.600.240
- E05.200.500.386
- E05.242.386
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
