Centromeric histone H3-like protein-2 Antibody, ALEXA FLUOR 555

  • Catalog number
    bs-0483R-A555
  • Price
    Please ask
  • Size
    100ul
  • Long name
    Centromeric histone H3-like protein-2 Antibody, ALEXA FLUOR 555 Conjugated
  • Also known as
    Anti-Centromeric histone H3-like protein-2 PAb ALEXA FLUOR 555
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 555
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    Centromeric histone H3-like protein-2
  • Specificity
    This is a highly specific antibody against Centromeric histone H3-like protein-2.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    KLH conjugated synthetic peptide derived from Brassica juncea Centromeric histone H3-like protein-2
  • Gene ID Number
    1058
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Plant
  • Cross reactive species details
    Brassica juncea
  • Background of the antigen
    Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    553nm/568nm
  • Synonyms
    centromere-specic H3 variant protein; Centromeric histone H3-like protein 2; Centromeric histone H3-like protein-2; cenp-A; A4P1_BRAJU.
  • Properties
    For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Conjugation
    Alexa Fluor, ALEXA FLUOR 555
  • French translation
    anticorps
  • Gene target
  • Gene symbol
    H3-7, H3C15, H3Y2, H3Y1, H3-4, H3C14, H3C11, H3-3A-DT, H3-5, RLN3
  • Short name
    Anti-Centromeric histone H3-like protein-2
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Immunoglobulin G (IgG)
  • Label
    ALEXA FLUOR 555
  • Alternative name
    Centromeric histone H3-like protein-2 Antibody, ALEXA FLUOR 555
  • Alternative technique
    antibodies
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    H3-3A divergent transcript
  • Locus
  • Discovery year
    2020-08-21
  • Classification
    • Divergent transcripts
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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