BACE2 Antibody , Cy5 Conjugated

• Catalog number
  bs-10494R-Cy5
• Price
  Please ask
• Size
  0.1ml

• Long name
  BACE2 Polyclonal Antibody , Cy5 Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  Cy5
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  BACE2
• Specificity
  This is a highly specific antibody against BACE2.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  345-375/518
• Subcellular location
  Extracellular
• Source
  KLH conjugated synthetic peptide derived from human BACE2
• Gene ID number
  25825
• Swiss Prot
  Q9Y5Z0
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  625,650nm/670nm
• Synonyms
  ASP1; BAE2; DRAP; AEPLC; ALP56; ASP21; CDA13; CEAP1; Beta-secretase 2; Aspartic-like protease 56 kDa; Aspartyl protease 1; Asp 1; Beta-site amyloid precursor protein cleaving enzyme 2; Beta-site APP cleaving enzyme 2; Down region aspartic protease; Memapsin-1; Membrane-associated aspartic protease 1; Theta-secretase; BACE2; UNQ418/PRO852
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor.
• Additional conjugation
  Cy5.5
• French translation
  anticorps

• Gene target
  BACE2   Conjugated  
• Gene symbol
  BACE2-IT1, BACE2
• Short name
  Anti-BACE2
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  Cy5
• Alternative name
  Anti-BACE2 PAb Cy5
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16024
• Gene
  BACE2-IT1
• Long gene name
  BACE2 intronic transcript 1
• Synonyms gene
  • C21orf75
  • NCRNA00228
• Synonyms gene name
  • chromosome 21 open reading frame 75
  • non-protein coding RNA 228
  • BACE2 intronic transcript 1 (non-protein coding)
• Synonyms
  • PRED43
• Locus
  21q22.2
• Discovery year
  2002-11-26
• Entrez gene record
  282569
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000086745

Gene info

• Identity
  HGNC:934
• Gene
  BACE2
• Long gene name
  beta-secretase 2
• Synonyms gene
  • AEPLC
• Synonyms gene name
  • beta-site APP-cleaving enzyme 2
• Synonyms
  • CEAP1
  • DRAP
  • ALP56
• Synonyms name
  • memapsin 1
• GenBank acession
  • AF117892
• Locus
  21q22.2-q22.3
• Discovery year
  2000-05-23
• Entrez gene record
  25825
• Pubmed identfication
  • 10965118
  • 10830953
• Classification
  • Peptidase family A1
• VEGA ID
  OTTHUMG00000086742

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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