ATG3 Antibody, HRP Conjugated

• Catalog number
  bs-4013R-HRP
• Price
  Please ask
• Size
  0.1ml

• Long name
  ATG3 Polyclonal Antibody, HRP Conjugated
• Category
  Conjugated Primary Antibodies
• Conjugation
  HRP
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  ATG3
• Specificity
  This is a highly specific antibody against ATG3.
• Modification
  Unmodified
• Modification site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen_range
  50-100/314
• Subcellular location
  Cytoplasm
• Source
  KLH conjugated synthetic peptide derived from human ATG3
• Gene ID number
  64422
• Swiss Prot
  Q9NT62
• Tested applications
  WB, IHC-P
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500)
• Crossreactivity
  Human, Mouse, Rat
• Crossreactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Antigen background
  E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8-like proteins from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8-like proteins. The formation of the ATG8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
• Excitation Emission
  N/A
• Synonyms
  APG3; APG3L; PC3-96; APG3-LIKE; Ubiquitin-like-conjugating enzyme ATG3; Autophagy-related protein 3; hApg3; Protein PC3-96; ATG3
• Properties
  If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
• Additional conjugation
  HRP Conjugated
• French translation
  anticorps

• Gene target
  ATG3   Conjugated  
• Gene symbol
  ATG3
• Short name
  Anti-ATG3
• Technique
  Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
• Isotype
  Immunoglobulin G (IgG)
• Label
  HRP
• Alternative name
  Anti-ATG3 PAb HRP
• Alternative technique
  antibodies
• Alternative to gene target
  autophagy related 3, ATG3 and IDBG-49891 and ENSG00000144848 and 64422, enzyme binding, Cytoplasm, Atg3 and IDBG-162821 and ENSMUSG00000022663 and 67841, ATG3 and IDBG-632300 and ENSBTAG00000009084 and 508571

Gene info

• Identity
  HGNC:20962
• Gene
  ATG3
• Long gene name
  autophagy related 3
• Synonyms gene
  • APG3L
• Synonyms gene name
  • APG3 autophagy 3-like (S. cerevisiae)
  • ATG3 autophagy related 3 homolog (S. cerevisiae)
• Synonyms
  • PC3-96
  • FLJ22125
  • MGC15201
  • DKFZp564M1178
• Locus
  3q13.2
• Discovery year
  2004-07-05
• Entrez gene record
  64422
• Pubmed identfication
  • 11825910
• RefSeq identity
  • NM_022488
• Classification
  • Autophagy related
• VEGA ID
  OTTHUMG00000159260

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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