PRK1 (Thr774)/PRK2 (Thr816) Antibody, ALEXA FLUOR 488

• Catalog number
  bs-3347R-A488
• Price
  Please ask
• Size
  100ul

• Long name
  PRK1 (Thr774)/PRK2 (Thr816) Antibody, ALEXA FLUOR 488 Conjugated
• Also known as
  Anti-PRK1 Thr774 + PRK2 Thr816 PAb ALEXA FLUOR 488
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 488
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  PRK1 Thr774 + PRK2 Thr816
• Specificity
  This is a highly specific antibody against PRK1 Thr774 + PRK2 Thr816.
• Modification
  Phosphorylation
• Modification Site
  Thr816
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from human PRK1 around the phosphorylation site of Thr774
• Gene ID Number
  5585
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) induces proliferation, migration, and fenestration in capillary endothelial cells derived from endocrine glands. EG-VEGF possesses an HIF-1 binding site; its expression is induced by hypoxia and restricted to the steroidogenic glands (ovary, testis, adrenal and placenta). Expression of EG-VEGF is often complementary to the expression of VEGF, suggesting that these molecules function in a coordinated manner. EG-VEGF is an example of a class of highly specific mitogens that act to regulate proliferation and differentiation of the vascular endothelium in a tissue-specific manner. It is expressed primarily in one type of tissue and acts selectively on one type of endothelium. EG-VEGF, possibly through binding to a G protein-coupled receptor, results in the activation of MAPK p44/42 and phosphatidylinositol 3-kinase signaling pathways, leading to proliferation, migration and survival of responsive endothelial cells .
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  499nm/519nm
• Synonyms
  Prokineticin-1/Endocrine-gland-derived vascular endothelial growth factor; PROK1; EGVEGF; PK1; EG-VEGF; PRK1.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-PRK1 Thr774 + PRK2 Thr816 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor
• French translation
  anticorps

• Gene target
  PRK1   Thr774   PRK2   Thr816  
• Gene symbol
  PROK1, PKN2, PKN1
• Short name
  Anti-PRK1 Thr774 + PRK2 Thr816
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 488
• Alternative name
  PRK1 (Thr774)/PRK2 (Thr816) Antibody, ALEXA FLUOR 488
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18454
• Gene
  PROK1
• Long gene name
  prokineticin 1
• Synonyms
  • PK1
  • PRK1
  • EGVEGF
• Synonyms name
  • black mamba toxin-related protein
  • mambakine
• GenBank acession
  • AF333024
• Locus
  1p13.3
• Discovery year
  2002-07-22
• Entrez gene record
  84432
• Pubmed identfication
  • 11259612
• RefSeq identity
  • NM_032414
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000011569

Gene info

• Identity
  HGNC:9406
• Gene
  PKN2
• Long gene name
  protein kinase N2
• Synonyms gene
  • PRKCL2
• Synonyms gene name
  • protein kinase C-like 2
• Synonyms
  • PRK2
  • Pak-2
  • STK7
• Synonyms name
  • cardiolipin-activated protein kinase Pak2
• GenBank acession
  • U33052
• Locus
  1p22.2
• Discovery year
  1997-10-10
• Entrez gene record
  5586
• Pubmed identfication
  • 7988719
  • 7851406
• RefSeq identity
  • NM_006256
• Classification
  • C2 domain containing protein kinases
  • AGC family kinases
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000010074

Gene info

• Identity
  HGNC:9405
• Gene
  PKN1
• Long gene name
  protein kinase N1
• Synonyms gene
  • PRKCL1
• Synonyms gene name
  • protein kinase C-like 1
• Synonyms
  • DBK
  • PRK1
  • PKN
  • MGC46204
  • PAK1
• GenBank acession
  • S75546
• Locus
  19p13.12
• Discovery year
  1997-10-10
• Entrez gene record
  5585
• Pubmed identfication
  • 9570957
• RefSeq identity
  • NM_002741
  • NM_213560
• Classification
  • C2 domain containing protein kinases
  • AGC family kinases
• VEGA ID
  OTTHUMG00000039611

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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