LDB1/CLIM-2 Antibody, ALEXA FLUOR 488
-
Catalog number
bs-11868R-A488
-
Price
Please ask
-
Size
100ul
-
-
Long name
LDB1/CLIM-2 Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
-
Also known as
Anti-LDB1/CLIM-2 PAb ALEXA FLUOR 488
-
Category
Conjugated Primary Antibodies
-
Conjugated with
ALEXA FLUOR® 488
-
Host Organism
Rabbit (Oryctolagus cuniculus)
-
Target Antigen
LDB1/CLIM-2
-
Specificity
This is a highly specific antibody against LDB1/CLIM-2.
-
Modification
Unmodified
-
Modification Site
None
-
Clonality
Polyclonal
-
Clone
Polyclonal antibody
-
Concentration
1ug per 1ul
-
Source
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LDB1/CLIM-2
-
Tested applications
IF(IHC-P)
-
Recommended dilutions
IF(IHC-P)(1:50-200)
-
Crossreactivity
Human, Mouse, Rat
-
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigen
The LIM-only (LMO) proteins, LMO1 and LMO2, are nuclear factors that are characterized by a conserved LIM domain. The LIM domain consists of a cysteine-rich zinc-binding motif that is present in a variety of transcription factors, including the LIM homeobox (LHX) proteins expressed in the central nervous system and involved in cell differentiation. LMO1 and LMO2 are expressed in the adult CNS in a cell type-specific manner, where they are differentially regulated by neuronal activity and are involved in regulating the cellular differentiated phenotype of neurons. LMO2 lacks a specific DNA-binding homeobox domain but rather assembles into transcriptional regulatory complexes to mediate gene expression by interacting with the widely expressed nuclear LIM interactor (NLI). NLI, known also as CLIM-1, and the related protein CLIM-2, facilitate the formation of heteromeric LIM complexes and also enhance the nuclear retention of LIM proteins. LMO2 and the related protein LMO4 are expressed in thymic precursor cells. LMO4 is also expressed in mature T cells, cranial neural crest cells, somite, dorsal limb bud mesenchyme, motor neurons, and Schwann cell progenitors.
-
Purification
Purified by Protein A.
-
Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission
499nm/519nm
-
Synonyms
Carboxyl Terminal LIM Domain Binding 2; Carboxyl-terminal LIM domain-binding protein 2; CLIM 2; CLIM-2; hLdb1; LDB-1; ldb1; LDB1_HUMAN; LIM Domain Binding 1; LIM domain binding factor CLIM2; LIM domain-binding factor CLIM2; LIM domain-binding protein 1; NLI; Nuclear LIM Domain Interactor; Nuclear LIM interactor antibodyxldb1.
-
Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-LDB1/CLIM-2 has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
Conjugation
Alexa Fluor
-
French translation
anticorps
-
Gene target
-
Gene symbol
LDB1, LDB2, MIR7-2, MIR329-2, MIR512-2, MIR521-2, MIR1289-2, MIR509-2, KRTAP13-2, RNU6-2
-
Short name
Anti-LDB1/CLIM-2
-
Technique
Antibody, antibodies against human proteins, antibodies for
-
Isotype
Immunoglobulin G (IgG)
-
Label
ALEXA FLUOR 488
-
Alternative name
LDB1/CLIM-2 Polyclonal Antibody, ALEXA FLUOR 488
-
Alternative technique
antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene name
LIM domain binding 1
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year
1999-01-22
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
LIM domain binding 2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year
1999-01-22
-
Entrez gene record
-
Pubmed identfication
-
Classification
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene name
microRNA 7-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year
2004-04-23
-
Entrez gene record
-
RefSeq identity
-
Classification
Gene info
-
Identity
-
Gene
-
Long gene name
microRNA 329-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year
2005-07-11
-
Entrez gene record
-
RefSeq identity
-
Classification
Gene info
-
Identity
-
Gene
-
Long gene name
microRNA 512-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year
2005-07-15
-
Entrez gene record
-
RefSeq identity
-
Classification
Gene info
-
Identity
-
Gene
-
Long gene name
microRNA 521-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year
2005-07-15
-
Entrez gene record
-
RefSeq identity
-
Classification
Gene info
-
Identity
-
Gene
-
Long gene name
microRNA 1289-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year
2008-11-03
-
Entrez gene record
-
RefSeq identity
-
Classification
Gene info
-
Identity
-
Gene
-
Long gene name
microRNA 509-2
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year
2007-10-24
-
Entrez gene record
-
RefSeq identity
-
Classification
Gene info
Gene info
-
Identity
-
Gene
-
Long gene name
RNA, U6 small nuclear 2
-
Synonyms
-
Locus
-
Discovery year
2008-06-10
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
MeSH Data
-
Name
-
Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
Similar products