IRE1a Antibody, ALEXA FLUOR 488
#
-
Catalog numberbs-8680R-A488
-
Price:
-
Size100ul
-
-
Long nameIRE1a Polyclonal Antibody, ALEXA FLUOR 488 Conjugated
-
Also known asAnti-IRE1a PAb ALEXA FLUOR 488
-
CategoryConjugated Primary Antibodies
-
Conjugated withALEXA FLUOR® 488
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenIRE1a
-
SpecificityThis is a highly specific antibody against IRE1a.
-
ModificationUnmodified
-
Modification SiteNone
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
Immunogen range250-300/977
-
Subcellular locationLumenal
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IRE1a
-
Gene ID Number2081
-
Swiss ProtO75460
-
Tested applicationsIF(IHC-P)
-
Recommended dilutionsIF(IHC-P)(1:50-200)
-
CrossreactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigenSenses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
-
PurificationPurified by Protein A.
-
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission499nm/519nm
-
SynonymsIRE1; IRE1P; IRE1a; hIRE1p; Serine/threonine-protein kinase/endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; Ire1-alpha; ERN1
-
PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), yet the Anti-IRE1a has a very high photo stability. As a result of this photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry. It is distinguished in the FL1 of a FACS-Calibur or FACScan. Also Alexa Fluor 488 is pH stable. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
ConjugationAlexa Fluor
-
French translationanticorps
-
Gene target
-
Short nameAnti-IRE1a
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 488
-
Alternative nameIRE1a Polyclonal Antibody, ALEXA FLUOR 488
-
Alternative techniqueantibodies
-
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data