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IRE1a Antibody, ALEXA FLUOR 555

  • Catalog number
    bs-8680R-A555
  • Product name
    IRE1a Antibody, ALEXA FLUOR 555
  • Size
    100ul
  • Short name
    Anti-IRE1a
  • Long name
    IRE1a Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
  • Also known as
    Anti-IRE1a PAb ALEXA FLUOR 555
  • Category
    Conjugated Primary Antibodies
  • Conjugated with
    ALEXA FLUOR® 555
  • Host Organism
    Rabbit (Oryctolagus cuniculus)
  • Target Antigen
    IRE1a
  • Specificity
    This is a highly specific antibody against IRE1a.
  • Modification
    Unmodified
  • Modification Site
    None
  • Clonality
    Polyclonal
  • Clone
    Polyclonal antibody
  • Isotype
    Immunoglobulin G (IgG)
  • Concentration
    1ug per 1ul
  • Immunogen range
    250-300/977
  • Subcellular location
    Lumenal
  • Source
    This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IRE1a
  • Gene ID Number
    2081
  • Swiss Prot
    O75460
  • Tested applications
    IF(IHC-P)
  • Recommended dilutions
    IF(IHC-P)(1:50-200)
  • Crossreactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the antigen
    Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
  • Purification
    Purified by Protein A.
  • Storage conditions
    Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
  • Excitation emission
    553nm/568nm
  • Synonyms
    IRE1; IRE1P; IRE1a; hIRE1p; Serine/threonine-protein kinase/endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; Ire1-alpha; ERN1
  • Gene target
    IRE1a
  • isotype filter
    • Immunoglobulin G IgG
  • Label
    ALEXA FLUOR 555
  • label filter
    • ALEXA FLUOR 555
  • technique filter
    • Antibody
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Alternative technique
    antibodies