Integrin Alpha V + Beta1 Antibody, ALEXA FLUOR 594
-
Catalog numberbs-2016R-A594
-
PricePlease ask
-
Size100ul
-
-
Long nameIntegrin Alpha V + Beta1 Antibody, ALEXA FLUOR 594 Conjugated
-
Also known asAnti-Integrin Alpha V + Beta 1 PAb ALEXA FLUOR 594
-
CategoryConjugated Primary Antibodies
-
Conjugated withALEXA FLUOR® 594
-
Host OrganismRabbit (Oryctolagus cuniculus)
-
Target AntigenIntegrin Alpha V + Beta 1
-
SpecificityThis is a highly specific antibody against Integrin Alpha V + Beta 1.
-
ModificationUnmodified
-
Modification SiteNone
-
ClonalityPolyclonal
-
ClonePolyclonal antibody
-
Concentration1ug per 1ul
-
Immunogen range1-38/1048
-
Subcellular locationExtracellular
-
SourceMixed KLH conjugated syntheticpeptides for human Integrin Alpha V and human Integrin Beta1
-
Gene ID Number3685, 3688
-
Tested applicationsIF(IHC-P)
-
Recommended dilutionsIF(IHC-P)(1:50-200)
-
CrossreactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the antigenThe alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro).
-
PurificationPurified by Protein A.
-
Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
-
Excitation emission590nm/617nm
-
SynonymsIntegrin alpha-V: Integrin alpha-V, Vitronectin receptor subunit alpha, CD51 Integrin beta-1: Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29
-
PropertiesFor facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
ConjugationAlexa Fluor, ALEXA FLUOR® 594
-
ConjugatedAlexa conjugate 1
-
DescriptionThe Anti-Integrin Alpha V + Beta 1 is a α- or alpha protein sometimes glycoprotein present in blood.
-
French translationanticorps
-
Gene target
-
Short nameAnti-Integrin Alpha V + Beta 1
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeImmunoglobulin G (IgG)
-
LabelALEXA FLUOR 594
-
Alternative nameIntegrin Alpha V + Beta1 Antibody, ALEXA FLUOR 594
-
Alternative techniqueantibodies
-
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data