- Catalog numberbs-1310R-A594
- Product nameIntegrin Alpha V + Beta 3 Antibody, ALEXA FLUOR 594
- Size100ul
- PriceAsk For Price
- Short nameAnti-Integrin Alpha V + Beta 3
- Long nameIntegrin Alpha V + Beta 3 Antibody, ALEXA FLUOR 594 Conjugated
- Also known asAnti-Integrin Alpha V + Beta 3 PAb ALEXA FLUOR 594
- CategoryConjugated Primary Antibodies
- Conjugated withALEXA FLUOR® 594
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenIntegrin Alpha V + Beta 3
- SpecificityThis is a highly specific antibody against Integrin Alpha V + Beta 3.
- ModificationUnmodified
- Modification SiteNone
- ClonalityPolyclonal
- ClonePolyclonal antibody
- IsotypeImmunoglobulin G (IgG)
- Concentration1ug per 1ul
- Subcellular locationExtracellular
- SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Integrin Alpha V + Beta 3
- Gene ID Number3690, 3685
- Swiss ProtP05106, P06756
- Tested applicationsFCM, IF(IHC-P)
- Recommended dilutionsFCM(1:20-100), IF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Background of the antigenITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
- PurificationPurified by Protein A.
- Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
- Excitation emission590nm/617nm
- SynonymsCD51; MSK8; VNRA; VTNR; Integrin alpha-V; Vitronectin receptor subunit alpha; ITGAV; CD61; GP3A; BDPLT2; GPIIIa; BDPLT16; Integrin beta-3; Platelet membrane glycoprotein IIIa; ITGB3
- Gene targetIntegrin Alpha V + Beta 3
- isotype filter
- Immunoglobulin G IgG
- LabelALEXA FLUOR 594
- label filter
- ALEXA FLUOR 594
- technique filter
- Antibody
- TechniqueAntibody, antibodies against human proteins, antibodies for
- Alternative techniqueantibodies