Integrin alpha 4/CD49d Antibody, ALEXA FLUOR 350
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Catalog numberbs-0641R-A350
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PricePlease ask
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Size100ul
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Long nameIntegrin alpha 4/CD49d Antibody, ALEXA FLUOR 350 Conjugated
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Also known asAnti-Integrin alpha 4/CD49d PAb ALEXA FLUOR 350
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 350
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenIntegrin alpha 4/CD49d
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SpecificityThis is a highly specific antibody against Integrin alpha 4/CD49d.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range584-609/1032
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Subcellular locationExtracellular
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Integrin alpha 4
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Gene ID Number3676
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Swiss ProtP13612
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Tested applicationsFCM, IF(IHC-P)
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Recommended dilutionsFCM(1:20-100), IF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat, Rabbit
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenIntegrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells.
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission343nm/442nm
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SynonymsIA4; CD49D; Integrin alpha-4; CD49 antigen-like family member D; Integrin alpha-IV; VLA-4 subunit alpha; ITGA4
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PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR 350
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DescriptionThe Anti-Integrin alpha 4/CD49d is a α- or alpha protein sometimes glycoprotein present in blood.
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French translationanticorps
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Gene target
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Gene symbolITGA4
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Short nameAnti-Integrin alpha 4/CD49d
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 350
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Alternative nameIntegrin alpha 4/CD49d Antibody, ALEXA FLUOR 350
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameintegrin subunit alpha 4
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Synonyms gene
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Synonyms gene name
- integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
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Synonyms
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Synonyms name
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Locus
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Discovery year1991-08-06
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Entrez gene record
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Pubmed identfication
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Classification
- CD molecules
- Integrin alpha subunits
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VEGA ID