EYA4 Antibody, ALEXA FLUOR 647

• Catalog number
  bs-13126R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  EYA4 Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-EYA4 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  EYA4
• Specificity
  This is a highly specific antibody against EYA4.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EYA4
• Gene ID Number
  2070
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  A gene of chromosome 6q23 encodes the 640 amino acid protein, EYA4 (eyes absent) (1). EYA is one of four members of the eyes absent family (1). A 271 amino acid domain at the carboxyl terminal is highly conserved amongst the members of the eyes absent family (1). EYA4 is expressed in the craniofacial mesenchyme, the dermamyotome, and the limb (1). The conserved region in other EYA proteins interacts with SIX, DACH, and G-proteins, which regulate transcription in early embryonic development (1,2,3,4). SIX translocates EYA1-3 to the nucleus, and G-proteins can stop this interaction (3,4). Premature stop codon mutations in EYA4 cause postlingual, progressive autosomal dominant hearing loss in humans (2). This shows that EYA4 is also vital to the mature organ of Corti (2). EYA4 may cause oculo-dento-digital syndrome, based on its expression pattern and map postion (1).
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  CMD1J; Deafness, autosomal dominant 10; DFNA 10; DFNA10; dJ78N10.1 eyes absent Drosophila homolog 4; dJ78N10.1 eyes absent; EYA 4; eya4; EYA4_HUMAN; Eyes absent 4; Eyes absent homolog 4 Drosophila; Eyes absent homolog 4; HGNC:3522; OTTHUMP00000040267.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-EYA4 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  EYA4  
• Gene symbol
  EYA4, TARID
• Short name
  Anti-EYA4
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  EYA4 Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:3522
• Gene
  EYA4
• Long gene name
  EYA transcriptional coactivator and phosphatase 4
• Synonyms gene
  • DFNA10
  • CMD1J
• Synonyms gene name
  • eyes absent (Drosophila) homolog 4
  • eyes absent homolog 4 (Drosophila)
• GenBank acession
  • Y17114
• Locus
  6q23.2
• Discovery year
  1998-07-15
• Entrez gene record
  2070
• Pubmed identfication
  • 9887327
  • 11159937
• RefSeq identity
  • NM_004100
• Classification
  • EYA transcriptional coactivator and phosphatases
• VEGA ID
  OTTHUMG00000015602
• Locus Specific Databases
  • Hereditary Hearing Loss Homepage
  • LRG_418

Gene info

• Identity
  HGNC:50506
• Gene
  TARID
• Long gene name
  TCF21 antisense RNA inducing promoter demethylation
• Synonyms gene
  • EYA4-AS1
• Synonyms gene name
  • EYA4 antisense RNA 1
• Locus
  6q23.2
• Discovery year
  2014-05-13
• Entrez gene record
  100507308
• Pubmed identfication
  • 25087872
• RefSeq identity
  • NR_109982
• Classification
  • Long non-coding RNAs with non-systematic symbols
• VEGA ID
  OTTHUMG00000015607

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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