EYA4 Antibody, ALEXA FLUOR 350
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Catalog numberbs-13126R-A350
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PricePlease ask
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Size100ul
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Long nameEYA4 Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
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Also known asAnti-EYA4 PAb ALEXA FLUOR 350
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 350
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenEYA4
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SpecificityThis is a highly specific antibody against EYA4.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EYA4
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Gene ID Number2070
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenA gene of chromosome 6q23 encodes the 640 amino acid protein, EYA4 (eyes absent) (1). EYA is one of four members of the eyes absent family (1). A 271 amino acid domain at the carboxyl terminal is highly conserved amongst the members of the eyes absent family (1). EYA4 is expressed in the craniofacial mesenchyme, the dermamyotome, and the limb (1). The conserved region in other EYA proteins interacts with SIX, DACH, and G-proteins, which regulate transcription in early embryonic development (1,2,3,4). SIX translocates EYA1-3 to the nucleus, and G-proteins can stop this interaction (3,4). Premature stop codon mutations in EYA4 cause postlingual, progressive autosomal dominant hearing loss in humans (2). This shows that EYA4 is also vital to the mature organ of Corti (2). EYA4 may cause oculo-dento-digital syndrome, based on its expression pattern and map postion (1).
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission343nm/442nm
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SynonymsCMD1J; Deafness, autosomal dominant 10; DFNA 10; DFNA10; dJ78N10.1 eyes absent Drosophila homolog 4; dJ78N10.1 eyes absent; EYA 4; eya4; EYA4_HUMAN; Eyes absent 4; Eyes absent homolog 4 Drosophila; Eyes absent homolog 4; HGNC:3522; OTTHUMP00000040267.
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PropertiesFor facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR 350
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French translationanticorps
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Gene target
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Gene symbolEYA4, TARID
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Short nameAnti-EYA4
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 350
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Alternative nameEYA4 Polyclonal Antibody, ALEXA FLUOR 350
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameEYA transcriptional coactivator and phosphatase 4
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Synonyms gene
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Synonyms gene name
- eyes absent (Drosophila) homolog 4
- eyes absent homolog 4 (Drosophila)
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GenBank acession
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Locus
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Discovery year1998-07-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- EYA transcriptional coactivator and phosphatases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameTCF21 antisense RNA inducing promoter demethylation
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Synonyms gene
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Synonyms gene name
- EYA4 antisense RNA 1
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Locus
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Discovery year2014-05-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Long non-coding RNAs with non-systematic symbols
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data