beta 2 Defensin Antibody, ALEXA FLUOR 647

• Catalog number
  bs-4307R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  beta 2 Defensin Polyclonal Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-beta 2 Defensin PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  beta 2 Defensin
• Specificity
  This is a highly specific antibody against beta 2 Defensin.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  34-64/64
• Subcellular location
  Secreted
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human beta 2 Defensin
• Gene ID Number
  1673
• Swiss Prot
  O15263
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  BD-2; SAP1; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB12; Beta-defensin 4A; Beta-defensin 2; Defensin, beta 2; Skin-antimicrobial peptide 1; DEFB4A
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-beta 2 Defensin exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• Description
  human, mouse or other beta β- and alpha α- defensins are expressed by neutrophils ( α- ), lymphocytes and epithelial cells. DEFA DEFB genes defend the host against pathogens. GENTAUR supplies anti-defensins, monclonals, polyclonals antisera and recombinant DEFs or peptides of defensin.
• French translation
  anticorps

• Gene target
  beta   Defensin  
• Gene symbol
  DEFB4A, DEFB4B, DEFB109E
• Short name
  Anti-beta 2 Defensin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  beta 2 Defensin Polyclonal Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2767
• Gene
  DEFB4A
• Long gene name
  defensin beta 4A
• Synonyms gene
  • DEFB102
  • DEFB2
  • DEFB4
• Synonyms gene name
  • defensin, beta 2
  • defensin, beta 4
  • defensin, beta 4A
• Synonyms
  • SAP1
  • HBD-2
  • DEFB-2
• Synonyms name
  • beta defensin 2
  • beta defensin-2
  • beta-defensin 2
• GenBank acession
  • AJ000152
• Locus
  8p23.1
• Discovery year
  1997-08-28
• Entrez gene record
  1673
• Pubmed identfication
  • 9202117
• RefSeq identity
  • NM_004942
• Classification
  • Receptor ligands
  • Defensins, beta
• VEGA ID
  OTTHUMG00000129314

Gene info

• Identity
  HGNC:30193
• Gene
  DEFB4B
• Long gene name
  defensin beta 4B
• Synonyms gene
  • DEFB4P
• Synonyms gene name
  • defensin, beta 4, pseudogene
  • defensin, beta 4B
• Synonyms name
  • beta defensin 2
  • beta defensin-2
  • beta-defensin 2
• Locus
  8p23.1
• Discovery year
  2005-02-25
• Entrez gene record
  100289462
• Classification
  • Defensins, beta
• VEGA ID
  OTTHUMG00000143857

Gene info

• Identity
  HGNC:30592
• Gene
  DEFB109E
• Long gene name
  defensin beta 109E (pseudogene)
• Synonyms gene
  • DEFB109P2
• Synonyms gene name
  • defensin, beta 109, pseudogene 2
  • defensin beta 109 pseudogene 2
• Locus
  8p23.1
• Discovery year
  2005-02-28
• Entrez gene record
  503839
• Classification
  • Defensins, beta

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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