beta 2 Defensin Antibody, ALEXA FLUOR 350

• Catalog number
  bs-4307R-A350
• Price
  Please ask
• Size
  100ul

• Long name
  beta 2 Defensin Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
• Also known as
  Anti-beta 2 Defensin PAb ALEXA FLUOR 350
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 350
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  beta 2 Defensin
• Specificity
  This is a highly specific antibody against beta 2 Defensin.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  34-64/64
• Subcellular location
  Secreted
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human beta 2 Defensin
• Gene ID Number
  1673
• Swiss Prot
  O15263
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  343nm/442nm
• Synonyms
  BD-2; SAP1; DEFB2; DEFB4; HBD-2; DEFB-2; DEFB12; Beta-defensin 4A; Beta-defensin 2; Defensin, beta 2; Skin-antimicrobial peptide 1; DEFB4A
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 350
• Description
  human, mouse or other beta β- and alpha α- defensins are expressed by neutrophils ( α- ), lymphocytes and epithelial cells. DEFA DEFB genes defend the host against pathogens. GENTAUR supplies anti-defensins, monclonals, polyclonals antisera and recombinant DEFs or peptides of defensin.
• French translation
  anticorps

• Gene target
  beta   Defensin  
• Gene symbol
  DEFB4A, DEFB4B, DEFB109E
• Short name
  Anti-beta 2 Defensin
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 350
• Alternative name
  beta 2 Defensin Polyclonal Antibody, ALEXA FLUOR 350
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2767
• Gene
  DEFB4A
• Long gene name
  defensin beta 4A
• Synonyms gene
  • DEFB102
  • DEFB2
  • DEFB4
• Synonyms gene name
  • defensin, beta 2
  • defensin, beta 4
  • defensin, beta 4A
• Synonyms
  • SAP1
  • HBD-2
  • DEFB-2
• Synonyms name
  • beta defensin 2
  • beta defensin-2
  • beta-defensin 2
• GenBank acession
  • AJ000152
• Locus
  8p23.1
• Discovery year
  1997-08-28
• Entrez gene record
  1673
• Pubmed identfication
  • 9202117
• RefSeq identity
  • NM_004942
• Classification
  • Receptor ligands
  • Defensins, beta
• VEGA ID
  OTTHUMG00000129314

Gene info

• Identity
  HGNC:30193
• Gene
  DEFB4B
• Long gene name
  defensin beta 4B
• Synonyms gene
  • DEFB4P
• Synonyms gene name
  • defensin, beta 4, pseudogene
  • defensin, beta 4B
• Synonyms name
  • beta defensin 2
  • beta defensin-2
  • beta-defensin 2
• Locus
  8p23.1
• Discovery year
  2005-02-25
• Entrez gene record
  100289462
• Classification
  • Defensins, beta
• VEGA ID
  OTTHUMG00000143857

Gene info

• Identity
  HGNC:30592
• Gene
  DEFB109E
• Long gene name
  defensin beta 109E (pseudogene)
• Synonyms gene
  • DEFB109P2
• Synonyms gene name
  • defensin, beta 109, pseudogene 2
  • defensin beta 109 pseudogene 2
• Locus
  8p23.1
• Discovery year
  2005-02-28
• Entrez gene record
  503839
• Classification
  • Defensins, beta

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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