Recombinant Human Melanoma antigen preferentially expressed in tumors (PRAME)

• Catalog number
  RPC21852-100ug
• Price
  Please ask
• Size
  100ug

• Estimated Turnaround Time
  3-5 weeks
• Gene Name
  PRAME
• Alternative Names
  Opa-interacting protein 4; OIP-4Preferentially expressed antigen of melanoma
• Source
  E.coli
• Purity
  > 90% by SDS-PAGE
• Shipping Conditions
  Ice packs
• Storage conditions
  Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
• Shelf life
  12 months in lyophilized form; 6 months in solution form.
• Restriction
  For research use only. Not for diagnostic procedures.
• Description
  Antigens are peptides or recombinant or native dependent on the production method.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Melanoma   preferentially   expressed   tumors   PRAME  
• Gene symbol
  PRAME
• Short name
  Recombinant Melanoma antigen preferentially expressed in tumors (PRAME)
• Technique
  Recombinant, antigen, antigenes, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biomatik advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Homo sapiens (Human), Humans
• Alternative name
  Rec. H. sapiens Melanoma protein preferentially expressed in tumors (preferentially expressed antigen in melanoma)
• Alternative technique
  rec, antigenes
• Alternative to gene target
  preferentially expressed antigen in melanoma, CT130 and MAPE and OIP-4 and OIP4, PRAME and IDBG-2240 and ENSG00000185686 and 23532, retinoic acid receptor binding, nuclei

Gene info

• Identity
  HGNC:9336
• Gene
  PRAME
• Long gene name
  PRAME nuclear receptor transcriptional regulator
• Synonyms gene
  • MAPE
• Synonyms gene name
  • preferentially expressed antigen in melanoma
• Synonyms
  • CT130
• Synonyms name
  • cancer/testis antigen 130
• GenBank acession
  • U65011
• Locus
  22q11.22
• Discovery year
  1996-06-21
• Entrez gene record
  23532
• Pubmed identfication
  • 9047241
  • 10591208
• RefSeq identity
  • NM_206953
• Classification
  • PRAME family
• VEGA ID
  OTTHUMG00000151172

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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