Recombinant Melanoma Cell Adhesion Molecule (MCAM)

• Catalog number
  RPU53834
• Price
  Please ask
• Size
  10 μg

• Verified reactivity
  Rattus norvegicus (Rat)
• Protein number
  Q9EPF2
• Gene name
  Please refer to GenBank
• Other name
  CD146; MUC18; Cell surface glycoprotein P1H12; Melanoma-associated antigen A32; S-endo 1 endothelial-associated antigen
• Protein origin
  E.coli
• Protein region
  Please contact us.
• Protein sequence
  Please contact us.
• Information about sequence
  Gln323~Lys560
• Expected molecular weight
  29,36kDa
• Protein purity
  ≥ 92%
• Verified applications
  SDS-PAGE; WB; ELISA; IP.
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  7-11 business days
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Description
  cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the Recombinant Melanoma Adhesion Molecule (MCAM). For cells, cell lines and tissues in culture till half confluency. Whole adhesion and interacting molecules are  present in lysates used as reference for ELISA quantification of these molecules and their subunits.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Melanoma   Adhesion   Molecule   MCAM  
• Gene symbol
  MCAM
• Short name
  Recombinant Melanoma Adhesion Molecule (MCAM)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. bioma advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Label
  two N-terminal Tags, His-tag and S-tag
• Alternative name
  Rec. Melanoma cellular Adhesion Molecule (melanoma cell adhesion molecule)
• Alternative technique
  rec
• Alternative to gene target
  melanoma cell adhesion molecule, CD146 and MUC18, MCAM and IDBG-74428 and ENSG00000076706 and 102465453,4162, protein binding, nuclei, Mcam and IDBG-155835 and ENSMUSG00000032135 and 84004, MCAM and IDBG-631776 and ENSBTAG00000006835 and 281301
• Tissue
  cell

Gene info

• Identity
  HGNC:6934
• Gene
  MCAM
• Long gene name
  melanoma cell adhesion molecule
• Synonyms
  • MUC18
  • CD146
  • MelCAM
  • METCAM
  • HEMCAM
• Synonyms name
  • Gicerin
• GenBank acession
  • X68264
• Locus
  11q23.3
• Discovery year
  1995-12-18
• Entrez gene record
  4162
• Pubmed identfication
  • 2602381
  • 10702685
  • 19229070
• Classification
  • Ig-like cell adhesion molecule family
  • C2-set domain containing
  • V-set domain containing
  • MicroRNA protein coding host genes
  • CD molecules
• VEGA ID
  OTTHUMG00000166197

MeSH Data

• Name
  Mammary Neoplasms, Experimental
• Concept
  Scope note: Experimentally induced mammary neoplasms in animals to provide a model for studying human BREAST NEOPLASMS.
• Tree numbers
  • C04.588.531.500
  • C04.619.590
  • E05.598.500.496.843
• Qualifiers
  diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, secondary, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, chemistry, psychology, urine, virology, history, blood supply, classification, economics, embryology, genetics, nursing, radiotherapy, prevention & control, pathology, ultrastructure, metabolism, complications, surgery

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