Leukemia inhibitory factor(LIF), OVA Conjugated

• Catalog number
  RPU50757
• Price
  Please ask
• Size
  100 μg

• Verified reactivity
  Sus scrofa; Porcine (Pig)
• Protein number
  Please refer to Uniprot
• Gene number
  Please refer to GenBank
• Other name
  CDF; D-FACTOR; HILDA; MLPLI; Cholinergic Differentiation Factor; Differentiation-Stimulating Factor; Melanoma-Derived LPL Inhibitor; Emfilermin
• Protein origin
  Peptide Synthesis
• Protein region
  Please contact us.
• Protein sequence
  Please contact us.
• Information about sequence
  Please contact us.
• Protein purity
  ≥ 90%
• Verified applications
  Immunogen; SDS-PAGE; WB
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  7-11 business days
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• Gene
  Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.

• Gene target
  Leukemia   inhibitory   factor   LIF   OVA   Conjugated  
• Gene symbol
  LIF-AS1, LIF-AS2, LIF
• Short name
  Leukemia inhibitory factor(LIF), OVA Conjugated
• Technique
  antibody Conjugates
• Label
  no tag
• Alternative name
  Leukemia inhibitory factor(leukemia inhibitory factor), OVA coupled
• Alternative to gene target
  leukemia inhibitory factor, CDF and DIA and HILDA and MLPLI, LIF and IDBG-3968 and ENSG00000128342 and 3976, growth factor activity, Extracellular, Lif and IDBG-142317 and ENSMUSG00000034394 and 16878, LIF and IDBG-636335 and ENSBTAG00000007424 and 280840
• Virus
  leukemia

Gene info

• Identity
  HGNC:53473
• Gene
  LIF-AS1
• Long gene name
  LIF antisense RNA 1
• Synonyms
  • Lnc-LIF-AS
• Locus
  22q12.2
• Discovery year
  2017-04-28
• Pubmed identfication
  • 28391028
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:28298
• Gene
  LIF-AS2
• Long gene name
  LIF antisense RNA 2
• Locus
  22q12.2
• Discovery year
  2020-10-07
• Entrez gene record
  91370
• RefSeq identity
  • NR_148946
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:6596
• Gene
  LIF
• Long gene name
  LIF interleukin 6 family cytokine
• Synonyms gene name
  • leukemia inhibitory factor
  • LIF, interleukin 6 family cytokine
• Synonyms
  • CDF
  • DIA
  • HILDA
• Synonyms name
  • differentiation inhibitory activity
  • differentiation-inducing factor
  • hepatocyte-stimulating factor III
  • cholinergic differentiation factor
  • human interleukin in DA cells
• Locus
  22q12.2
• Discovery year
  1989-06-11
• Entrez gene record
  3976
• Pubmed identfication
  • 1714745
  • 8058719
• RefSeq identity
  • NM_002309
• Classification
  • Receptor ligands
  • Interleukin 6 type cytokine family
• VEGA ID
  OTTHUMG00000150910
• Locus Specific Databases
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

MeSH Data

• Name
  Leukemia, Experimental
• Concept
  Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
• Tree numbers
  • C04.557.337.372
  • C04.619.531
  • E05.598.500.496.500
• Qualifiers
  diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery

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