ACVRL1 Polyclonal Antibody

• Catalog number
  CAC08094
• Price
  Please ask
• Size
  100 μg

• Other name
  Serine/threonine-protein kinase receptor R3,Activin receptor-like kinase 1,ALK-1,TGF-B superfamily receptor type I,TSR-I,ACVRL1,ACVRLK1,ALK1
• Immunogen
  Recombinant human Serine/threonine-protein kinase receptor R3 protein (22-118AA)
• Verified reactivity
  Human
• Verified applications
  ELISA,WB,IF
• Raised in
  Rabbit
• Clonality
  Polyclonal
• Protein number
  P37023
• Gene number
  Please refer to GenBank
• NCBI number
  Please refer to NCBI
• Purity
  Protein G purified, >95%
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  3-7 business days
• Supplementary information
  Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Properties
  If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  ACVRL1  
• Gene symbol
  ACVRL1
• Short name
  ACVRL1 Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  Unconjugated
• Alternative name
  activin A receptor classification II-like 1 polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  activin A receptor type II-like 1, ACVRLK1 and ALK-1 and ALK1 and HHT and HHT2 and ORW2 and SKR3 and TSR-I, ACVRL1 and IDBG-33826 and ENSG00000139567 and 102723650,94, transforming growth factor beta receptor activity, Cell surfaces, Acvrl1 and IDBG-185502 and ENSMUSG00000000530 and 11482, BT.28710 and IDBG-632173 and ENSBTAG00000013843 and 534536

Gene info

• Identity
  HGNC:175
• Gene
  ACVRL1
• Long gene name
  activin A receptor like type 1
• Synonyms gene
  • ACVRLK1
  • ORW2
• Synonyms gene name
  • activin A receptor type II-like 1
  • activin A receptor type IL
• Synonyms
  • HHT2
  • ALK1
  • HHT
• Synonyms name
  • activin receptor-like kinase 1
• GenBank acession
  • L17075
• Locus
  12q13.13
• Discovery year
  1994-12-12
• Entrez gene record
  94
• Pubmed identfication
  • 8397373
  • 8640225
  • 22718755
• RefSeq identity
  • NM_000020
• Classification
  • Type 1 receptor serine/threonine kinases
• VEGA ID
  OTTHUMG00000169507
• Locus Specific Databases
  • Hereditary Hemorrhagic Telangiectasia (HHT) Mutation Database
  • LRG_543

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products