LEP (116-130) (mouse)

Description

Leptin is a hormone that acts as a major regulator for food intake and energy homeostasis. Leptin deficiency or resistance can result in profound obesity, diabetes, and infertility.
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Formula

C64H109N19O24S
Molecular Weight

1560.73
Cas no

258276-95-8
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus

Gene target

LEP 116-130
Gene symbol

OR7E43P, LEP, FYB1, WASHC3, HDDC2, RRBP1, TCIRG1
Short name

LEP (116-130) (mouse)
Technique

Mouse, mouses
Host

mouse
Species

Mouse, Mouses
Alternative name

leptin (116-130) (mouse)
Alternative technique

murine
Alternative to gene target

leptin, LEPD and OB and OBS, LEP and IDBG-39587 and ENSG00000174697 and 3952, peptide hormone receptor binding, Extracellular, Lep and IDBG-130781 and ENSMUSG00000059201 and 16846, OBESE and IDBG-635003 and ENSBTAG00000014911 and 280836

Identity

HGNC:8417
Gene

OR7E43P
Long gene name

olfactory receptor family 7 subfamily E member 43 pseudogene
Synonyms gene name
- olfactory receptor, family 7, subfamily E, member 43 pseudogene
Synonyms
- OR4-116
GenBank acession
- U86267
Locus

4p16.3
Discovery year

1999-11-29
Entrez gene record

26475
Pubmed identfication
- 9500546
Classification
- Olfactory receptors, family 7
VEGA ID

OTTHUMG00000159869

Identity

HGNC:6553
Gene

LEP
Long gene name

leptin
Synonyms gene
- OBS
- OB
Synonyms gene name
- leptin (murine obesity homolog)
- leptin (obesity homolog, mouse)
Locus

7q32.1
Discovery year

1993-01-26
Entrez gene record

3952
Pubmed identfication
- 1686014
- 16932309
Classification
- Neuropeptides
VEGA ID

OTTHUMG00000157564

Identity

HGNC:10448
Gene

RRBP1
Long gene name

ribosome binding protein 1
Synonyms gene name
- ribosome binding protein 1 (dog 180kD homolog)
- ribosome binding protein 1 homolog 180kDa (dog)
Synonyms
- ES/130
- hES
- p180
Synonyms name
- ribosomal receptor-binding protein 1
- endoplasmic reticulum ribosome-binding protein 1
GenBank acession
- AB037819
Locus

20p12.1
Discovery year

1998-03-20
Entrez gene record

6238
Pubmed identfication
RefSeq identity
- NM_001042576
VEGA ID

OTTHUMG00000031945

Identity

HGNC:11647
Gene

TCIRG1
Long gene name

T cell immune regulator 1, ATPase H+ transporting V0 subunit a3
Synonyms gene name
- T-cell, immune regulator 1
- T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein a isoform 3
- T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
- T-cell immune regulator 1, ATPase H+ transporting V0 subunit a3
Synonyms
- TIRC7
- OC-116
- OC116
- ATP6N1C
- Atp6i
- a3
- ATP6V0A3
Synonyms name
- T-cell immune response cDNA 7
- V-ATPase subunit a3
GenBank acession
- AF025374
Locus

11q13.2
Discovery year

1999-02-15
Entrez gene record

10312
Pubmed identfication
- 8579597
- 9806637
RefSeq identity
- NM_006019
Classification
- V-type ATPase subunits
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000167358
Locus Specific Databases
- TCIRG1base: Mutation registry for autosomal recessive osteopetrosis
- LRG_115