immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus]

  • Catalog number
    A1072-25
  • Price
    Please ask
  • Size
    25mg
  • Description
    The immunoglobulin light chain is the small polypeptide subunit of an antibody ( immunoglobulin). The approximate length of a light chain protein is from 211 to 217 amino acids. Increased levels of free Ig light chains have also been detected in various inflammatory diseases. Very recent studies have shown that Ig light chains not only activate mast cells but also dorsal root ganglia and neutrophils, expanding their possible role as mediators in inflammatory disease.
  • Formula
    C54H83N13O13
  • Molecular Weight
    1122.32
  • Additional description
    Human proteins from Homo sapiens human species. Homo is the human genus, which also includes Neanderthals and many other extinct species of hominids. Specific human epitopes are selected for human ELISA kits.
  • Gene target
  • Short name
    immunoglobulin light chain variable region [ ]/[Mus musculus]
  • Technique
    light
  • Isotype
    Antibody fragments and scFv fragments, single chain variable fragments can be E. coli expressed. Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small. IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion. Complement fragments, bp DNA fragments are common.
  • Alternative name
    immunoglobulin light epitope variable region fragment [Homo sapiens]/[Mus musculus]
  • Tissue
    region
MeSH Data
  • Name
  • Concept
    Scope note: Radioimmunoassay of proteins using antibody coupled to an immunosorbent.
  • Tree numbers
    • E05.478.566.380.830
    • E05.478.566.639.830
    • E05.601.470.380.830
    • E05.601.470.639.830
  • Qualifiers
    ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data
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