immunoglobulin light chain variable region fragment [Homo sapiens]

• Catalog number
  A1071-10
• Price
  Please ask
• Size
  10mg

• Description
  The immunoglobulin light chain is the small polypeptide subunit of an antibody ( immunoglobulin). The approximate length of a light chain protein is from 211 to 217 amino acids. Increased levels of free Ig light chains have also been detected in various inflammatory diseases. Very recent studies have shown that Ig light chains not only activate mast cells but also dorsal root ganglia and neutrophils, expanding their possible role as mediators in inflammatory disease.
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• Formula
  C40H69N11O10
• Molecular Weight
  864.04
• Additional description
  Human proteins from Homo sapiens human species. Homo is the human genus, which also includes Neanderthals and many other extinct species of hominids. Specific human epitopes are selected for human ELISA kits.

• Gene target
  immunoglobulin   light   chain   variable   region  
• Short name
  immunoglobulin light chain variable region [ ]
• Technique
  light
• Isotype
  Antibody fragments and scFv fragments, single chain variable fragments can be E. coli expressed. Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small. IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion. Complement fragments, bp DNA fragments are common.
• Alternative name
  immunoglobulin light epitope variable region fragment [Homo sapiens]
• Tissue
  region

MeSH Data

• Name
  Radioallergosorbent Test
• Concept
  Scope note: An in vitro allergen radioimmunoassay in which allergens are coupled to an immunosorbent. The coupled allergens bind the IgE in the sera of patients which in turn binds radioisotope-labeled anti-IMMUNOGLOBULIN E antibodies.
• Tree numbers
  • E01.370.225.812.735.830
  • E05.200.812.735.830
  • E05.478.566.380.810
  • E05.478.566.639.810
  • E05.478.594.760.830
  • E05.601.470.380.810
  • E05.601.470.639.810
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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