CD59, MAC Inhibitor, Hematopoietic and non-Hematopoietic Cell, gp18-20, Clone: MEM 43, Mouse Monoclonal antibody-Human, azide-free
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Catalog numberYSRTMCA1054XZ
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Price:
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Size1 mg
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Alternative name 1CD59, MAC Inhibitor, Hematopoietic and non-Hematopoietic Cell, gp18-20, Clone: MEM 43, Mab anti-Human, azide-free
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Alternative name 2CD59, MAC Inhibitor, Hematopoietic and non-Hematopoietic Cell, gp18-20, Clone: MEM 43, Mab antibody-Human, azide-free
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Alternative name 3CD59, MAC Inhibitor, Hematopoietic and non-Hematopoietic Cell, gp18-20, Clone: MEM 43, Mab antibody-Homo sapiens, azide-free
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Alternative name 4anti-CD59 MAC Inhibitor Hematopoietic and non-Hematopoietic Cell gp18-20 Clone: MEM 43
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Alternative name 5CD59 MAC Inhibitor Hematopoietic and non-Hematopoietic Cell gp18-20 Clone: MEM 43
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ClonalityMonoclonal Antibody
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DescriptionThis is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against. If used correctly and according the protocol, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications. Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches; in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required.
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Storage and handlingGenerally, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for longer periods - at -20 . Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°C.
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AdvisoryTo keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided. For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container. Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom.
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PropertiesIf you buy Antibodies supplied by accurate-monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional descriptionSodium azide NaN3 is often used to prevent antibody degradation in 0,02% W/V concentrations. accurate-monoclonals supplies azide free antibodies on request. For cells, cell lines and tissues in culture till half confluency. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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French translationanticorps
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Gene target
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Gene symbolLGALS3, ITGAM, ITGB2, LGALS3BP, CD59
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Short nameCD59, MAC Inhibitor, Hematopoietic non-Hematopoietic , gp18-20, Clone: MEM 43, Mouse Monoclonal antibody- , -free
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TechniqueMouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Hostmouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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SpeciesHuman, Humans, Mouses
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Alternative nameCD59 molecule, complement regulatory protein, MAC suppressor, Hematopoietic and non-Hematopoietic cellular, gp18-20, clonality: MEM 43, Mouse monoclonal (antibody to-)-H. sapiens, azide-free
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Alternative techniqueantibodies, murine
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Alternative to gene targetCD59 molecule, complement regulatory protein, 16.3A5 and 1F5 and EJ16 and EJ30 and EL32 and G344 and HRF-20 and HRF20 and MAC-IP and MACIF and MEM43 and MIC11 and MIN1 and MIN2 and MIN3 and MIRL and MSK21 and p18-20, CD59 and IDBG-38813 and ENSG00000085063 and 966, protein binding, Extracellular, CD59 and IDBG-636427 and ENSBTAG00000002302 and 505574
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Tissuecell
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Gene info
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Identity
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Gene
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Long gene namegalectin 3
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Synonyms gene
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Synonyms gene name
- lectin, galactoside-binding, soluble, 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1991-09-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
- Galectins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameintegrin subunit alpha M
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Synonyms gene
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Synonyms gene name
- integrin, alpha M (complement component receptor 3, alpha; also known as CD11b (p170), macrophage antigen alpha polypeptide)
- integrin, alpha M (complement component 3 receptor 3 subunit)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1988-08-05
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Entrez gene record
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RefSeq identity
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Classification
- Integrin alpha subunits
- Complement system regulators and receptors
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameintegrin subunit beta 2
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Synonyms gene
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Synonyms gene name
- integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
- integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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RefSeq identity
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Classification
- Integrin beta subunits
- Complement system regulators and receptors
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namegalectin 3 binding protein
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Synonyms gene name
- lectin, galactoside-binding, soluble, 3 binding protein
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1994-09-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BTB domain containing
- Scavenger receptor cysteine rich domain containing
- Receptor ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCD59 molecule (CD59 blood group)
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Synonyms gene
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Synonyms gene name
- CD59 antigen p18-20 (antigen identified by monoclonal antibodies 16.3A5, EJ16, EJ30, EL32 and G344)
- CD59 antigen, complement regulatory protein
- CD59 molecule, complement regulatory protein
- CD59 molecule
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Synonyms
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Locus
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Discovery year1989-06-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Blood group antigens
- Complement system regulators and receptors
- CD molecules
- LY6/PLAUR domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data