ONO-4059

  • Catalog number
    B1283-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    (R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one
  • Description
    ONO-4059 is a highly selective, orally bioavailable BTK (Bruton’s Tyrosine Kinase) inhibitor with a potency an IC₅₀ of 2.2 nM.
  • CAS Number
    1351636-18-4
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₅H₂₂N₆O₃
  • Molecular Weight
    454.48
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>5 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A highly selective, orally bioavailable BTK (Bruton’s Tyrosine Kinase) inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    54755438
  • SMILES
    CC#CC(=O)N1CCC(C1)N2C3=C(C(=NC=N3)N)N(C2=O)C4=CC=C(C=C4)OC5=CC=CC=C5
  • InChi
    InChI=1S/C25H22N6O3/c1-2-6-21(32)29-14-13-18(15-29)31-24-22(23(26)27-16-28-24)30(25(31)33)17-9-11-20(12-10-17)34-19-7-4-3-5-8-19/h3-5,7-12,16,18H,13-15H2,1H3,(H2,26,27,28)/t18-/m1/s1
  • InChi Key
    SEJLPXCPMNSRAM-GOSISDBHSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    ONO-4059
  • Alternative name
    ONO-4059
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