ONO-4059
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Catalog numberB1283-5
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PricePlease ask
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Size5 mg
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Alternative_name(R)-6-amino-9-(1-(but-2-ynoyl)pyrrolidin-3-yl)-7-(4-phenoxyphenyl)-7,9-dihydro-8H-purin-8-one
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DescriptionONO-4059 is a highly selective, orally bioavailable BTK (Bruton’s Tyrosine Kinase) inhibitor with a potency an IC₅₀ of 2.2 nM.
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CAS Number1351636-18-4
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₅H₂₂N₆O₃
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Molecular Weight454.48
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>5 mg/ml)
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HandlingProtect from air and light
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Tag LineA highly selective, orally bioavailable BTK (Bruton’s Tyrosine Kinase) inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID54755438
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SMILESCC#CC(=O)N1CCC(C1)N2C3=C(C(=NC=N3)N)N(C2=O)C4=CC=C(C=C4)OC5=CC=CC=C5
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InChiInChI=1S/C25H22N6O3/c1-2-6-21(32)29-14-13-18(15-29)31-24-22(23(26)27-16-28-24)30(25(31)33)17-9-11-20(12-10-17)34-19-7-4-3-5-8-19/h3-5,7-12,16,18H,13-15H2,1H3,(H2,26,27,28)/t18-/m1/s1
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InChi KeySEJLPXCPMNSRAM-GOSISDBHSA-N
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MSDS AvailableYes
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Gene target
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Short nameONO-4059
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Alternative nameONO-4059
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