Erlotinib, Hydrochloride, Free Base, EGFR Inhibitor (CP-358774, OSI-774, Ro 50-8231)

• Catalog number
  MBS6030386
• Price
  Please ask
• Size
  100 mg

• Other size
  please contact us to order other different size
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

• Gene target
  Erlotinib   Hydrochloride   Free   Base   EGFR   Inhibitor   CP-358774   OSI-774   50-8231  
• Gene symbol
  CP, EGFR-AS1, IGLV1-50, CEMP1, IGHV3-50, EGILA, EGFR, DCTN2, GAP43, RNU6-50P
• Short name
  Erlotinib, Hydrochloride, Free Base, EGFR Inhibitor (CP-358774, OSI-774, Ro 50-8231)
• Alternative name
  Erlotinib, Hydrochloride, Free Base, epidermal growth factor receptor suppressor (CP-358774, OSI-774, Ro 50-8231)
• Alternative to gene target
  epidermal growth factor receptor, ERBB and ERBB1 and HER1 and mENA and PIG61, EGFR and IDBG-16933 and ENSG00000146648 and 1956, transferase activity, nuclei, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217

Gene info

• Identity
  HGNC:2295
• Gene
  CP
• Long gene name
  ceruloplasmin
• Synonyms gene name
  • ceruloplasmin (ferroxidase)
• Synonyms name
  • ferroxidase
• GenBank acession
  • M13536
• Locus
  3q24-q25.1
• Discovery year
  1986-01-01
• Entrez gene record
  1356
• RefSeq identity
  • NM_000096
• VEGA ID
  OTTHUMG00000159563

Gene info

• Identity
  HGNC:40207
• Gene
  EGFR-AS1
• Long gene name
  EGFR antisense RNA 1
• Locus
  7p11.2
• Discovery year
  2012-11-06
• Entrez gene record
  100507500
• Pubmed identfication
  • 26271667
  • 28920960
• RefSeq identity
  • NR_047551
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000156126

Gene info

• Identity
  HGNC:5881
• Gene
  IGLV1-50
• Long gene name
  immunoglobulin lambda variable 1-50 (non-functional)
• Synonyms gene name
  • immunoglobulin lambda variable 1-50
• GenBank acession
  • M94112
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28821
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151051

Gene info

• Identity
  HGNC:32553
• Gene
  CEMP1
• Long gene name
  cementum protein 1
• Synonyms
  • CP-23
• Synonyms name
  • cementum protein-23
• GenBank acession
  • AY584596
• Locus
  16p13.3
• Discovery year
  2006-09-19
• Entrez gene record
  752014
• Pubmed identfication
  • 16263347
• RefSeq identity
  • NM_001048212
• VEGA ID
  OTTHUMG00000177160

Gene info

• Identity
  HGNC:5608
• Gene
  IGHV3-50
• Long gene name
  immunoglobulin heavy variable 3-50 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable 3-50
  • immunoglobulin heavy variable 3-50 pseudogene
• GenBank acession
  • M99677
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28422
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000151964

Gene info

• Identity
  HGNC:54482
• Gene
  EGILA
• Long gene name
  EGFR interacting lncRNA
• Synonyms
  • Lnc-EGFR
• Locus
  14q11.2
• Discovery year
  2019-09-27
• Pubmed identfication
  • 28541302
• Classification
  • Long non-coding RNAs with non-systematic symbols

Gene info

• Identity
  HGNC:3236
• Gene
  EGFR
• Long gene name
  epidermal growth factor receptor
• Synonyms gene
  • ERBB
• Synonyms gene name
  • epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
• Synonyms
  • ERBB1
  • ERRP
• Synonyms name
  • erythroblastic leukemia viral (v-erb-b) oncogene homolog (avian)
  • erb-b2 receptor tyrosine kinase 1
• Locus
  7p11.2
• Discovery year
  1986-01-01
• Entrez gene record
  1956
• Pubmed identfication
  • 1505215
• RefSeq identity
  • NM_005228
• Classification
  • Erb-b2 receptor tyrosine kinases
• VEGA ID
  OTTHUMG00000023661
• Locus Specific Databases
  • LRG_304

Gene info

• Identity
  HGNC:2712
• Gene
  DCTN2
• Long gene name
  dynactin subunit 2
• Synonyms gene name
  • dynactin 2 (p50)
• Synonyms
  • RBP50
  • DCTN-50
• GenBank acession
  • U50733
• Locus
  12q13.3
• Discovery year
  1995-10-03
• Entrez gene record
  10540
• Pubmed identfication
  • 8647893
• RefSeq identity
  • NM_006400
• Classification
  • Dynactin subunits
• VEGA ID
  OTTHUMG00000170124

Gene info

• Identity
  HGNC:4140
• Gene
  GAP43
• Long gene name
  growth associated protein 43
• Synonyms
  • B-50
  • PP46
  • GAP-43
• Synonyms name
  • neuron growth-associated protein 43
  • neuromodulin
  • nerve growth-related peptide GAP43
  • axonal membrane protein GAP-43
  • protein F1
  • calmodulin-binding protein P-57
  • neural phosphoprotein B-50
• Locus
  3q13.31
• Discovery year
  1990-07-10
• Entrez gene record
  2596
• Pubmed identfication
  • 3272162
  • 8231732
• RefSeq identity
  • NM_002045
• VEGA ID
  OTTHUMG00000133758

Gene info

• Identity
  HGNC:10229
• Gene
  RNU6-50P
• Long gene name
  RNA, U6 small nuclear 50, pseudogene
• Synonyms gene
  • RNU6P1
  • RNU6-50
• Synonyms gene name
  • RNA, U6 small nuclear pseudogene 1
  • RNA, U6 small nuclear 50
• Synonyms
  • U6
• GenBank acession
  • K03026
• Locus
  Xp11.3
• Discovery year
  1999-12-14
• Entrez gene record
  26825
• Pubmed identfication
  • 2998934
• RefSeq identity
  • NG_001248

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