DPPIV (Mouse) Antibody

  • Catalog number
    6694-50
  • Price
    Please ask
  • Size
    50 μg
  • Antibody Target
    DPPIV
  • Target Alternative Name
    DPP4, DPP-4, ADABP, ADCP2, ADCP-2, CD26, CD-26, DPPIV, DPPIV, TP103, TP-103
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Mouse
  • Immunogen Sequence
    Mouse myeloma cell line NS0-derived recombinant mouse DPPIV/CD26
  • Accession
    P28843
  • Gene Id
    13482
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Concentration
    0.2 mg/ml
  • Formulation
    0.2 mg/ml in PBS
  • Purification
    Antigen affinity purified
  • Application
    Western Blot, IHC
  • Positive Control
    Western Blot, IHC
  • Application And Usages
    WB: 0.1 µg/ml, IHC: 5-15 µg/ml
  • Description
    Dipeptidyl peptidase-IV (DPPIV), also known as adenosine deaminase complexing protein 2, DPPIV or CD26 is antigenic enzyme expressed on the surface of most cell types and is associated with immune regulation, signal transduction and apoptosis. It is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. The substrates of DPPIV are proline (or alanine)-containing peptides and include growth factors, chemokines, neuropeptides, and vasoactive peptides. DPPIV plays a major role in glucose metabolism. It is responsible for the degradation of incretins such as GLP-1. DPPIV plays an important role in tumor biology, and is useful as a marker for various cancers, with its levels either on the cell surface or in the serum increased in some neoplasms and decreased in others. DPPIV also binds the enzyme adenosine deaminase specifically and with high affinity. The significance of this interaction has yet to be established.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Dot Blot Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • Test
    Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
  • Latin name
    Mus musculus
  • French translation
    anticorps
  • Gene target
    DPPIV  
  • Gene symbol
    FAP, DPP4
  • Short name
    DPPIV (Mouse) Antibody
  • Technique
    Antibody, Mouse, antibodies against human proteins, antibodies for, mouses
  • Host
    mouse
  • Isotype
    Goat IgG
  • Species
    Mouse, Mouses
  • Alternative name
    DPPIV (Mouse) (antibody to-)
  • Alternative technique
    antibodies, murine
Gene info
Gene info
  • Identity
  • Gene
  • Long gene name
    dipeptidyl peptidase 4
  • Synonyms gene
  • Synonyms gene name
    • dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)
    • adenosine deaminase complexing protein 2
    • dipeptidyl-peptidase 4
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1990-03-05
  • Entrez gene record
  • Pubmed identfication
  • Classification
    • CD molecules
    • DASH family
  • VEGA ID
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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